1urw
From Proteopedia
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[[Image:1urw.png|left|200px]] | [[Image:1urw.png|left|200px]] | ||
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{{STRUCTURE_1urw| PDB=1urw | SCENE= }} | {{STRUCTURE_1urw| PDB=1urw | SCENE= }} | ||
===CDK2 IN COMPLEX WITH AN IMIDAZO[1,2-B]PYRIDAZINE=== | ===CDK2 IN COMPLEX WITH AN IMIDAZO[1,2-B]PYRIDAZINE=== | ||
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==See Also== | ==See Also== | ||
| - | *[[Cell Division Protein Kinase 2]] | + | *[[Cell Division Protein Kinase 2|Cell Division Protein Kinase 2]] |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:015081018</ref><ref group="xtra">PMID:008917641</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
Revision as of 17:53, 26 July 2012
Contents |
CDK2 IN COMPLEX WITH AN IMIDAZO[1,2-B]PYRIDAZINE
Template:ABSTRACT PUBMED 15081018
About this Structure
1urw is a 1 chain structure of Cell Division Protein Kinase 2 with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Byth KF, Cooper N, Culshaw JD, Heaton DW, Oakes SE, Minshull CA, Norman RA, Pauptit RA, Tucker JA, Breed J, Pannifer A, Rowsell S, Stanway JJ, Valentine AL, Thomas AP. Imidazo[1,2-b]pyridazines: a potent and selective class of cyclin-dependent kinase inhibitors. Bioorg Med Chem Lett. 2004 May 3;14(9):2249-52. PMID:15081018 doi:10.1016/j.bmcl.2004.02.008
- Schulze-Gahmen U, De Bondt HL, Kim SH. High-resolution crystal structures of human cyclin-dependent kinase 2 with and without ATP: bound waters and natural ligand as guides for inhibitor design. J Med Chem. 1996 Nov 8;39(23):4540-6. PMID:8917641 doi:10.1021/jm960402a
Categories: Homo sapiens | Non-specific serine/threonine protein kinase | Breed, J. | Byth, K F. | Cooper, N. | Culshaw, J D. | Heaton, D W. | Minshull, C A. | Norman, R A. | Oakes, S E. | Pannifer, A. | Pauptit, R A. | Rowsell, S. | Stanway, J J. | Thomas, A P. | Tucker, J A. | Valentine, A L. | Mitosis | Serine/threonine-protein kinase | Transferase
