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3ipb

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Image:3ipb.png

Template:STRUCTURE 3ipb

Contents

Human Transthyretin (TTR) complexed with a palindromic bivalent amyloid inhibitor (11 carbon linker).

Template:ABSTRACT PUBMED 21059958

About this Structure

3ipb is a 2 chain structure of Transthyretin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Kolstoe SE, Mangione PP, Bellotti V, Taylor GW, Tennent GA, Deroo S, Morrison AJ, Cobb AJ, Coyne A, McCammon MG, Warner TD, Mitchell J, Gill R, Smith MD, Ley SV, Robinson CV, Wood SP, Pepys MB. Trapping of palindromic ligands within native transthyretin prevents amyloid formation. Proc Natl Acad Sci U S A. 2010 Nov 8. PMID:21059958 doi:10.1073/pnas.1008255107

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OCA

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