1w8u

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(New page: 200px<br /> <applet load="1w8u" size="450" color="white" frame="true" align="right" spinBox="true" caption="1w8u, resolution 1.30&Aring;" /> '''CBM29-2 MUTANT D83A...)
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==About this Structure==
==About this Structure==
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1W8U is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Piromyces_equi Piromyces equi]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1W8U OCA]].
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1W8U is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Piromyces_equi Piromyces equi]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1W8U OCA]].
==Reference==
==Reference==
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[[Category: mannohexaose]]
[[Category: mannohexaose]]
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Oct 29 21:23:07 2007''
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 13:58:35 2007''

Revision as of 11:53, 30 October 2007


1w8u, resolution 1.30Å

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CBM29-2 MUTANT D83A COMPLEXED WITH MANNOHEXAOSE: PROBING THE MECHANISM OF LIGAND RECOGNITION BY FAMILY 29 CARBOHYDRATE BINDING MODULES

Overview

The recycling of photosynthetically fixed carbon, by the action of, microbial plant cell wall hydrolases, is integral to one of the major, geochemical cycles and is of considerable industrial importance., Non-catalytic carbohydrate-binding modules (CBMs) play a key role in this, degradative process by targeting hydrolytic enzymes to their cognate, substrate within the complex milieu of polysaccharides that comprise the, plant cell wall. Family 29 CBMs have, thus far, only been found in an, extracellular multienzyme plant cell wall-degrading complex from the, anaerobic fungus Piromyces equi, where they exist as a CBM29-1:CBM29-2, tandem. Here we present both the structure of the CBM29-1 partner, at 1.5, A resolution, and examine the importance of hydrophobic stacking, interactions as well ... [(full description)]

About this Structure

1W8U is a [Single protein] structure of sequence from [Piromyces equi]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].

Reference

Probing the mechanism of ligand recognition in family 29 carbohydrate-binding modules., Flint J, Bolam DN, Nurizzo D, Taylor EJ, Williamson MP, Walters C, Davies GJ, Gilbert HJ, J Biol Chem. 2005 Jun 24;280(25):23718-26. Epub 2005 Mar 22. PMID:15784618

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