3ckp

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{{Seed}}
 
[[Image:3ckp.png|left|200px]]
[[Image:3ckp.png|left|200px]]
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{{STRUCTURE_3ckp| PDB=3ckp | SCENE= }}
{{STRUCTURE_3ckp| PDB=3ckp | SCENE= }}
===Crystal structure of BACE-1 in complex with inhibitor===
===Crystal structure of BACE-1 in complex with inhibitor===
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{{ABSTRACT_PUBMED_18434152}}
{{ABSTRACT_PUBMED_18434152}}
==About this Structure==
==About this Structure==
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3CKP is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CKP OCA].
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[[3ckp]] is a 3 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CKP OCA].
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==See Also==
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*[[Beta secretase|Beta secretase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:18434152</ref><references group="xtra"/>
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<ref group="xtra">PMID:018434152</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Memapsin 2]]
[[Category: Memapsin 2]]
[[Category: Min, K.]]
[[Category: Min, K.]]
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[[Category: Alternative splicing]]
 
[[Category: Aspartyl protease]]
[[Category: Aspartyl protease]]
[[Category: Beta-secretase]]
[[Category: Beta-secretase]]
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[[Category: Transmembrane]]
[[Category: Transmembrane]]
[[Category: Zymogen]]
[[Category: Zymogen]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 13:33:13 2009''
 

Revision as of 18:34, 26 July 2012

Template:STRUCTURE 3ckp

Contents

Crystal structure of BACE-1 in complex with inhibitor

Template:ABSTRACT PUBMED 18434152

About this Structure

3ckp is a 3 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Park H, Min K, Kwak HS, Koo KD, Lim D, Seo SW, Choi JU, Platt B, Choi DY. Synthesis, SAR, and X-ray structure of human BACE-1 inhibitors with cyclic urea derivatives. Bioorg Med Chem Lett. 2008 May 1;18(9):2900-4. Epub 2008 Apr 8. PMID:18434152 doi:10.1016/j.bmcl.2008.03.081

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