3gzn
From Proteopedia
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[[Image:3gzn.png|left|200px]] | [[Image:3gzn.png|left|200px]] | ||
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===Structure of NEDD8-activating enzyme in complex with NEDD8 and MLN4924=== | ===Structure of NEDD8-activating enzyme in complex with NEDD8 and MLN4924=== | ||
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==See Also== | ==See Also== | ||
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==Reference== | ==Reference== |
Revision as of 18:51, 26 July 2012
Contents |
Structure of NEDD8-activating enzyme in complex with NEDD8 and MLN4924
Template:ABSTRACT PUBMED 20129059
About this Structure
3gzn is a 6 chain structure of NEDD8 with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Brownell JE, Sintchak MD, Gavin JM, Liao H, Bruzzese FJ, Bump NJ, Soucy TA, Milhollen MA, Yang X, Burkhardt AL, Ma J, Loke HK, Lingaraj T, Wu D, Hamman KB, Spelman JJ, Cullis CA, Langston SP, Vyskocil S, Sells TB, Mallender WD, Visiers I, Li P, Claiborne CF, Rolfe M, Bolen JB, Dick LR. Substrate-assisted inhibition of ubiquitin-like protein-activating enzymes: the NEDD8 E1 inhibitor MLN4924 forms a NEDD8-AMP mimetic in situ. Mol Cell. 2010 Jan 15;37(1):102-11. PMID:20129059 doi:10.1016/j.molcel.2009.12.024