3inh

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Revision as of 18:57, 26 July 2012

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Template:STRUCTURE 3inh

Contents 1 Bace1 with the aminohydantoin Compound R-58 2 About this Structure 3 See Also 4 Reference

Bace1 with the aminohydantoin Compound R-58

Template:ABSTRACT PUBMED 19968289

About this Structure

3inh is a 1 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Beta secretase

Reference

• Malamas MS, Erdei J, Gunawan I, Turner J, Hu Y, Wagner E, Fan K, Chopra R, Olland A, Bard J, Jacobsen S, Magolda RL, Pangalos M, Robichaud AJ. Design and synthesis of 5,5'-disubstituted aminohydantoins as potent and selective human beta-secretase (BACE1) inhibitors. J Med Chem. 2010 Feb 11;53(3):1146-58. PMID:19968289 doi:10.1021/jm901414e