3hp5
From Proteopedia
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[[Image:3hp5.png|left|200px]] | [[Image:3hp5.png|left|200px]] | ||
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{{STRUCTURE_3hp5| PDB=3hp5 | SCENE= }} | {{STRUCTURE_3hp5| PDB=3hp5 | SCENE= }} | ||
===Crystal Structure of Human p38alpha complexed with a pyrimidopyridazinone compound=== | ===Crystal Structure of Human p38alpha complexed with a pyrimidopyridazinone compound=== | ||
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{{ABSTRACT_PUBMED_19751974}} | {{ABSTRACT_PUBMED_19751974}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3hp5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HP5 OCA]. | + | [[3hp5]] is a 1 chain structure of [[Mitogen-activated protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HP5 OCA]. |
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| + | ==See Also== | ||
| + | *[[Mitogen-activated protein kinase|Mitogen-activated protein kinase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019751974</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Mitogen-activated protein kinase]] | [[Category: Mitogen-activated protein kinase]] | ||
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[[Category: Stegeman, R A.]] | [[Category: Stegeman, R A.]] | ||
[[Category: Williams, J M.]] | [[Category: Williams, J M.]] | ||
| + | [[Category: Atp-binding]] | ||
| + | [[Category: Distal and extra sites. peptide flip]] | ||
| + | [[Category: Kinase]] | ||
| + | [[Category: Nucleotide-binding]] | ||
| + | [[Category: Nucleus]] | ||
| + | [[Category: Phosphoprotein]] | ||
| + | [[Category: Serine/threonine-protein kinase]] | ||
| + | [[Category: Three binding site]] | ||
| + | [[Category: Three ligand]] | ||
| + | [[Category: Transferase]] | ||
| + | [[Category: Two lobe]] | ||
Revision as of 18:58, 26 July 2012
Contents |
Crystal Structure of Human p38alpha complexed with a pyrimidopyridazinone compound
Template:ABSTRACT PUBMED 19751974
About this Structure
3hp5 is a 1 chain structure of Mitogen-activated protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Selness SR, Devraj RV, Monahan JB, Boehm TL, Walker JK, Devadas B, Durley RC, Kurumbail R, Shieh H, Xing L, Hepperle M, Rucker PV, Jerome KD, Benson AG, Marrufo LD, Madsen HM, Hitchcock J, Owen TJ, Christie L, Promo MA, Hickory BS, Alvira E, Naing W, Blevis-Bal R. Discovery of N-substituted pyridinones as potent and selective inhibitors of p38 kinase. Bioorg Med Chem Lett. 2009 Oct 15;19(20):5851-6. Epub 2009 Aug 27. PMID:19751974 doi:10.1016/j.bmcl.2009.08.082
Categories: Homo sapiens | Mitogen-activated protein kinase | Kurumbail, R G. | Shieh, H S. | Stegeman, R A. | Williams, J M. | Atp-binding | Distal and extra sites. peptide flip | Kinase | Nucleotide-binding | Nucleus | Phosphoprotein | Serine/threonine-protein kinase | Three binding site | Three ligand | Transferase | Two lobe
