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3drr
From Proteopedia
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[[Image:3drr.png|left|200px]] | [[Image:3drr.png|left|200px]] | ||
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{{STRUCTURE_3drr| PDB=3drr | SCENE= }} | {{STRUCTURE_3drr| PDB=3drr | SCENE= }} | ||
===HIV reverse transcriptase Y181C mutant in complex with inhibitor R8e=== | ===HIV reverse transcriptase Y181C mutant in complex with inhibitor R8e=== | ||
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{{ABSTRACT_PUBMED_18826204}} | {{ABSTRACT_PUBMED_18826204}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3drr]] is a 2 chain structure of [[Reverse transcriptase]] with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DRR OCA]. | |
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| + | ==See Also== | ||
| + | *[[Reverse transcriptase|Reverse transcriptase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018826204</ref><references group="xtra"/> |
[[Category: Human immunodeficiency virus 1]] | [[Category: Human immunodeficiency virus 1]] | ||
[[Category: Yan, Y.]] | [[Category: Yan, Y.]] | ||
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[[Category: Nucleotidyltrasferase]] | [[Category: Nucleotidyltrasferase]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
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Revision as of 19:07, 26 July 2012
Contents |
HIV reverse transcriptase Y181C mutant in complex with inhibitor R8e
Template:ABSTRACT PUBMED 18826204
About this Structure
3drr is a 2 chain structure of Reverse transcriptase with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.
See Also
Reference
- Tucker TJ, Sisko JT, Tynebor RM, Williams TM, Felock PJ, Flynn JA, Lai MT, Liang Y, McGaughey G, Liu M, Miller M, Moyer G, Munshi V, Perlow-Poehnelt R, Prasad S, Reid JC, Sanchez R, Torrent M, Vacca JP, Wan BL, Yan Y. Discovery of 3-{5-[(6-Amino-1H-pyrazolo[3,4-b]pyridine-3-yl)methoxy]-2-chlorophenoxy}-5 -chlorobenzonitrile (MK-4965): A Potent, Orally Bioavailable HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitor with Improved Potency against Key Mutant Viruses. J Med Chem. 2008 Oct 1. PMID:18826204 doi:10.1021/jm800856c
