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2py4

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Image:2py4.png

Template:STRUCTURE 2py4

Contents

Full length structure of the Mycobacterium tuberculosis dUTPase complexed with magnesium and alpha,beta-imido-dUTP.

Template:ABSTRACT PUBMED 18519027

About this Structure

2py4 is a 1 chain structure of Deoxyuridine 5'-triphosphate nucleotidohydrolase with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.

See Also

Reference

  • Varga B, Barabas O, Takacs E, Nagy N, Nagy P, Vertessy BG. Active site of mycobacterial dUTPase: structural characteristics and a built-in sensor. Biochem Biophys Res Commun. 2008 Aug 15;373(1):8-13. Epub 2008 Jun 2. PMID:18519027 doi:10.1016/j.bbrc.2008.05.130
  • Vertessy BG, Toth J. Keeping uracil out of DNA: physiological role, structure and catalytic mechanism of dUTPases. Acc Chem Res. 2009 Jan 20;42(1):97-106. PMID:18837522 doi:10.1021/ar800114w

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