1hxw
From Proteopedia
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[[Image:1hxw.png|left|200px]] | [[Image:1hxw.png|left|200px]] | ||
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{{STRUCTURE_1hxw| PDB=1hxw | SCENE= }} | {{STRUCTURE_1hxw| PDB=1hxw | SCENE= }} | ||
===HIV-1 PROTEASE DIMER COMPLEXED WITH A-84538=== | ===HIV-1 PROTEASE DIMER COMPLEXED WITH A-84538=== | ||
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{{ABSTRACT_PUBMED_7708670}} | {{ABSTRACT_PUBMED_7708670}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[1hxw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. The June 2000 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''HIV-1 Protease'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2000_6 10.2210/rcsb_pdb/mom_2000_6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HXW OCA]. | + | [[1hxw]] is a 2 chain structure of [[Virus protease]] with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. The June 2000 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''HIV-1 Protease'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2000_6 10.2210/rcsb_pdb/mom_2000_6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HXW OCA]. |
==See Also== | ==See Also== | ||
| - | *[[Demonstration of a complex animation playing from a green link]] | + | *[[Demonstration of a complex animation playing from a green link|Demonstration of a complex animation playing from a green link]] |
| - | *[[Ritonavir]] | + | *[[Molecular Playground/HIV Protease Inhibitor|Molecular Playground/HIV Protease Inhibitor]] |
| + | *[[Ritonavir|Ritonavir]] | ||
| + | *[[Virus protease|Virus protease]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:007708670</ref><references group="xtra"/> |
[[Category: HIV-1 Protease]] | [[Category: HIV-1 Protease]] | ||
[[Category: HIV-1 retropepsin]] | [[Category: HIV-1 retropepsin]] | ||
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[[Category: Hiv]] | [[Category: Hiv]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
| + | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
Revision as of 19:31, 26 July 2012
Contents |
HIV-1 PROTEASE DIMER COMPLEXED WITH A-84538
Template:ABSTRACT PUBMED 7708670
About this Structure
1hxw is a 2 chain structure of Virus protease with sequence from Human immunodeficiency virus 1. The June 2000 RCSB PDB Molecule of the Month feature on HIV-1 Protease by David S. Goodsell is 10.2210/rcsb_pdb/mom_2000_6. Full crystallographic information is available from OCA.
See Also
- Demonstration of a complex animation playing from a green link
- Molecular Playground/HIV Protease Inhibitor
- Ritonavir
- Virus protease
Reference
- Kempf DJ, Marsh KC, Denissen JF, McDonald E, Vasavanonda S, Flentge CA, Green BE, Fino L, Park CH, Kong XP, et al.. ABT-538 is a potent inhibitor of human immunodeficiency virus protease and has high oral bioavailability in humans. Proc Natl Acad Sci U S A. 1995 Mar 28;92(7):2484-8. PMID:7708670
