1t7i

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{{STRUCTURE_1t7i| PDB=1t7i | SCENE= }}
{{STRUCTURE_1t7i| PDB=1t7i | SCENE= }}
===The structural and thermodynamic basis for the binding of TMC114, a next-generation HIV-1 protease inhibitor.===
===The structural and thermodynamic basis for the binding of TMC114, a next-generation HIV-1 protease inhibitor.===
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{{ABSTRACT_PUBMED_15771427}}
{{ABSTRACT_PUBMED_15771427}}
==About this Structure==
==About this Structure==
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1T7I is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T7I OCA].
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[[1t7i]] is a 2 chain structure of [[Virus protease]] with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T7I OCA].
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==See Also==
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*[[Virus protease|Virus protease]]
==Reference==
==Reference==
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<ref group="xtra">PMID:15771427</ref><references group="xtra"/>
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<ref group="xtra">PMID:015771427</ref><references group="xtra"/>
[[Category: HIV-1 retropepsin]]
[[Category: HIV-1 retropepsin]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
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[[Category: Drug resitance]]
[[Category: Drug resitance]]
[[Category: Hiv-1 protease]]
[[Category: Hiv-1 protease]]
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[[Category: Hydrolase]]
[[Category: Substrate envelope]]
[[Category: Substrate envelope]]
[[Category: Thermodynamic]]
[[Category: Thermodynamic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 14:15:02 2009''
 

Revision as of 19:34, 26 July 2012

Template:STRUCTURE 1t7i

Contents

The structural and thermodynamic basis for the binding of TMC114, a next-generation HIV-1 protease inhibitor.

Template:ABSTRACT PUBMED 15771427

About this Structure

1t7i is a 2 chain structure of Virus protease with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

See Also

Reference

  • Surleraux DL, Tahri A, Verschueren WG, Pille GM, de Kock HA, Jonckers TH, Peeters A, De Meyer S, Azijn H, Pauwels R, de Bethune MP, King NM, Prabu-Jeyabalan M, Schiffer CA, Wigerinck PB. Discovery and selection of TMC114, a next generation HIV-1 protease inhibitor. J Med Chem. 2005 Mar 24;48(6):1813-22. PMID:15771427 doi:10.1021/jm049560p

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