2xbw
From Proteopedia
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[[Image:2xbw.png|left|200px]] | [[Image:2xbw.png|left|200px]] | ||
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{{STRUCTURE_2xbw| PDB=2xbw | SCENE= }} | {{STRUCTURE_2xbw| PDB=2xbw | SCENE= }} | ||
===Factor Xa in complex with a pyrrolidine-3,4-dicarboxylic acid inhibitor=== | ===Factor Xa in complex with a pyrrolidine-3,4-dicarboxylic acid inhibitor=== | ||
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==See Also== | ==See Also== | ||
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==Reference== | ==Reference== | ||
Revision as of 19:55, 26 July 2012
Contents |
Factor Xa in complex with a pyrrolidine-3,4-dicarboxylic acid inhibitor
Template:ABSTRACT PUBMED 20650636
About this Structure
2xbw is a 2 chain structure of Factor Xa with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Anselm L, Banner DW, Benz J, Zbinden KG, Himber J, Hilpert H, Huber W, Kuhn B, Mary JL, Otteneder MB, Panday N, Ricklin F, Stahl M, Thomi S, Haap W. Discovery of a factor Xa inhibitor (3R,4R)-1-(2,2-difluoro-ethyl)-pyrrolidine-3,4-dicarboxylic acid 3-[(5-chloro-pyridin-2-yl)-amide] 4-[[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)-phenyl]-amide] as a clinical candidate. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5313-9. Epub 2010 Jul 1. PMID:20650636 doi:10.1016/j.bmcl.2010.06.126
