2wc0
From Proteopedia
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Contents |
CRYSTAL STRUCTURE OF HUMAN INSULIN DEGRADING ENZYME IN COMPLEX WITH IODINATED INSULIN
Template:ABSTRACT PUBMED 19321446
About this Structure
2wc0 is a 6 chain structure of Insulin-Degrading Enzyme and Molecular Playground/Insulin with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Manolopoulou M, Guo Q, Malito E, Schilling AB, Tang WJ. Molecular basis of catalytic chamber-assisted unfolding and cleavage of human insulin by human insulin-degrading enzyme. J Biol Chem. 2009 May 22;284(21):14177-88. Epub 2009 Mar 25. PMID:19321446 doi:10.1074/jbc.M900068200
Categories: Homo sapiens | Insulysin | Guo, Q. | Malito, E. | Manolopoulou, M. | Schilling, A B. | Tang, W J. | Carbohydrate metabolism | Cleavage on pair of basic residue | Dioxane | Disulfide bond | Glucose metabolism | Hormone | Human insulin-degrading enzyme | Hydrolase | Hydrolase-hormone complex | Hydrolase/hormone | Insulin | Metal-binding | Metalloprotease | Protease | Secreted