3nlx
From Proteopedia
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| - | [[Image:3nlx. | + | [[Image:3nlx.png|left|200px]] |
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{{STRUCTURE_3nlx| PDB=3nlx | SCENE= }} | {{STRUCTURE_3nlx| PDB=3nlx | SCENE= }} | ||
===Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(((3R,4R)-4-(2- (2,2-Difluoro-2-(3-fluorophenyl)ethylamino)ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine=== | ===Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(((3R,4R)-4-(2- (2,2-Difluoro-2-(3-fluorophenyl)ethylamino)ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine=== | ||
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{{ABSTRACT_PUBMED_20843082}} | {{ABSTRACT_PUBMED_20843082}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3nlx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NLX OCA]. | + | [[3nlx]] is a 2 chain structure of [[Nitric Oxide Synthase]] with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NLX OCA]. |
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| + | ==See Also== | ||
| + | *[[Nitric Oxide Synthase|Nitric Oxide Synthase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:020843082</ref><references group="xtra"/> |
[[Category: Nitric-oxide synthase]] | [[Category: Nitric-oxide synthase]] | ||
[[Category: Rattus norvegicus]] | [[Category: Rattus norvegicus]] | ||
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[[Category: Li, H.]] | [[Category: Li, H.]] | ||
[[Category: Poulos, T L.]] | [[Category: Poulos, T L.]] | ||
| + | [[Category: Heme thiolate enzyme]] | ||
| + | [[Category: Inhibitor]] | ||
| + | [[Category: Nitric oxide synthase]] | ||
| + | [[Category: Oxidoreductase]] | ||
Revision as of 20:34, 26 July 2012
Contents |
Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(((3R,4R)-4-(2- (2,2-Difluoro-2-(3-fluorophenyl)ethylamino)ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine
Template:ABSTRACT PUBMED 20843082
About this Structure
3nlx is a 2 chain structure of Nitric Oxide Synthase with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.
See Also
Reference
- Xue F, Li H, Delker SL, Fang J, Martasek P, Roman LJ, Poulos TL, Silverman RB. Potent, highly selective, and orally bioavailable gem-difluorinated monocationic inhibitors of neuronal nitric oxide synthase. J Am Chem Soc. 2010 Oct 13;132(40):14229-38. PMID:20843082 doi:10.1021/ja106175q
