2cbn
From Proteopedia
(New page: 200px<br /> <applet load="2cbn" size="450" color="white" frame="true" align="right" spinBox="true" caption="2cbn, resolution 2.9Å" /> '''CRYSTAL STRUCTURE OF...) |
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==About this Structure== | ==About this Structure== | ||
| - | 2CBN is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]] with ZN as [[http://en.wikipedia.org/wiki/ligand ligand]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.26.11 3.1.26.11]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2CBN OCA]]. | + | 2CBN is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]] with ZN as [[http://en.wikipedia.org/wiki/ligand ligand]]. Active as [[http://en.wikipedia.org/wiki/Ribonuclease_Z Ribonuclease Z]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.26.11 3.1.26.11]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2CBN OCA]]. |
==Reference== | ==Reference== | ||
The crystal structure of the zinc phosphodiesterase from Escherichia coli provides insight into function and cooperativity of tRNase Z-family proteins., Kostelecky B, Pohl E, Vogel A, Schilling O, Meyer-Klaucke W, J Bacteriol. 2006 Feb;188(4):1607-14. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16452444 16452444] | The crystal structure of the zinc phosphodiesterase from Escherichia coli provides insight into function and cooperativity of tRNase Z-family proteins., Kostelecky B, Pohl E, Vogel A, Schilling O, Meyer-Klaucke W, J Bacteriol. 2006 Feb;188(4):1607-14. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16452444 16452444] | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
| + | [[Category: Ribonuclease Z]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Kostelecky, B.]] | [[Category: Kostelecky, B.]] | ||
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[[Category: zinc]] | [[Category: zinc]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 14:00:31 2007'' |
Revision as of 11:55, 30 October 2007
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CRYSTAL STRUCTURE OF ZIPD FROM ESCHERICHIA COLI
Overview
The elaC gene product from Escherichia coli, ZiPD, is a 3' tRNA-processing, endonuclease belonging to the tRNase Z family of enzymes that have been, identified in a wide variety of organisms. In contrast to the elaC, homologue from Bacillus subtilis, E. coli elaC is not essential for, viability, and although both enzymes process only precursor tRNA, (pre-tRNA) lacking a CCA triplet at the 3' end in vitro, the physiological, role of ZiPD remains enigmatic because all pre-tRNA species in E. coli are, transcribed with the CCA triplet. We present the first crystal structure, of ZiPD determined by multiple anomalous diffraction at a resolution of, 2.9 A. This structure shares many features with the tRNase Z enzymes from, B. subtilis and Thermotoga maritima, but there are distinct differences ... [(full description)]
About this Structure
2CBN is a [Single protein] structure of sequence from [Escherichia coli] with ZN as [ligand]. Active as [Ribonuclease Z], with EC number [3.1.26.11]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].
Reference
The crystal structure of the zinc phosphodiesterase from Escherichia coli provides insight into function and cooperativity of tRNase Z-family proteins., Kostelecky B, Pohl E, Vogel A, Schilling O, Meyer-Klaucke W, J Bacteriol. 2006 Feb;188(4):1607-14. PMID:16452444
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