2ywp
From Proteopedia
(Difference between revisions)
Line 1: | Line 1: | ||
- | {{Seed}} | ||
[[Image:2ywp.png|left|200px]] | [[Image:2ywp.png|left|200px]] | ||
- | <!-- | ||
- | The line below this paragraph, containing "STRUCTURE_2ywp", creates the "Structure Box" on the page. | ||
- | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
- | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
- | or leave the SCENE parameter empty for the default display. | ||
- | --> | ||
{{STRUCTURE_2ywp| PDB=2ywp | SCENE= }} | {{STRUCTURE_2ywp| PDB=2ywp | SCENE= }} | ||
===Crystal Structure of CHK1 with a Urea Inhibitor=== | ===Crystal Structure of CHK1 with a Urea Inhibitor=== | ||
- | |||
- | <!-- | ||
- | The line below this paragraph, {{ABSTRACT_PUBMED_16446090}}, adds the Publication Abstract to the page | ||
- | (as it appears on PubMed at http://www.pubmed.gov), where 16446090 is the PubMed ID number. | ||
- | --> | ||
{{ABSTRACT_PUBMED_16446090}} | {{ABSTRACT_PUBMED_16446090}} | ||
==About this Structure== | ==About this Structure== | ||
- | + | [[2ywp]] is a 1 chain structure of [[Serine/threonine protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2fga 2fga]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YWP OCA]. | |
+ | |||
+ | ==See Also== | ||
+ | *[[Serine/threonine protein kinase|Serine/threonine protein kinase]] | ||
==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:016446090</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
[[Category: Park, C.]] | [[Category: Park, C.]] | ||
[[Category: Protein-inhibitor complex]] | [[Category: Protein-inhibitor complex]] | ||
- | + | [[Category: Transferase]] | |
- | + |
Revision as of 21:26, 26 July 2012
Contents |
Crystal Structure of CHK1 with a Urea Inhibitor
Template:ABSTRACT PUBMED 16446090
About this Structure
2ywp is a 1 chain structure of Serine/threonine protein kinase with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 2fga. Full crystallographic information is available from OCA.
See Also
Reference
- Li G, Hasvold LA, Tao ZF, Wang GT, Gwaltney SL 2nd, Patel J, Kovar P, Credo RB, Chen Z, Zhang H, Park C, Sham HL, Sowin T, Rosenberg SH, Lin NH. Synthesis and biological evaluation of 1-(2,4,5-trisubstituted phenyl)-3-(5-cyanopyrazin-2-yl)ureas as potent Chk1 kinase inhibitors. Bioorg Med Chem Lett. 2006 Apr 15;16(8):2293-8. Epub 2006 Jan 30. PMID:16446090 doi:10.1016/j.bmcl.2006.01.028