1h01
From Proteopedia
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[[Image:1h01.png|left|200px]] | [[Image:1h01.png|left|200px]] | ||
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{{STRUCTURE_1h01| PDB=1h01 | SCENE= }} | {{STRUCTURE_1h01| PDB=1h01 | SCENE= }} | ||
===CDK2 IN COMPLEX WITH A DISUBSTITUTED 2, 4-BIS ANILINO PYRIMIDINE CDK4 INHIBITOR=== | ===CDK2 IN COMPLEX WITH A DISUBSTITUTED 2, 4-BIS ANILINO PYRIMIDINE CDK4 INHIBITOR=== | ||
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==See Also== | ==See Also== | ||
| - | *[[Cell Division Protein Kinase 2]] | + | *[[Cell Division Protein Kinase 2|Cell Division Protein Kinase 2]] |
==Reference== | ==Reference== | ||
Revision as of 21:42, 26 July 2012
Contents |
CDK2 IN COMPLEX WITH A DISUBSTITUTED 2, 4-BIS ANILINO PYRIMIDINE CDK4 INHIBITOR
Template:ABSTRACT PUBMED 12941311
About this Structure
1h01 is a 1 chain structure of Cell Division Protein Kinase 2 with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Beattie JF, Breault GA, Ellston RP, Green S, Jewsbury PJ, Midgley CJ, Naven RT, Minshull CA, Pauptit RA, Tucker JA, Pease JE. Cyclin-dependent kinase 4 inhibitors as a treatment for cancer. Part 1: identification and optimisation of substituted 4,6-bis anilino pyrimidines. Bioorg Med Chem Lett. 2003 Sep 15;13(18):2955-60. PMID:12941311
- Schulze-Gahmen U, De Bondt HL, Kim SH. High-resolution crystal structures of human cyclin-dependent kinase 2 with and without ATP: bound waters and natural ligand as guides for inhibitor design. J Med Chem. 1996 Nov 8;39(23):4540-6. PMID:8917641 doi:10.1021/jm960402a
