3c7p
From Proteopedia
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[[Image:3c7p.png|left|200px]] | [[Image:3c7p.png|left|200px]] | ||
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{{STRUCTURE_3c7p| PDB=3c7p | SCENE= }} | {{STRUCTURE_3c7p| PDB=3c7p | SCENE= }} | ||
===Crystal structure of human carbonic anhydrase II in complex with STX237=== | ===Crystal structure of human carbonic anhydrase II in complex with STX237=== | ||
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{{ABSTRACT_PUBMED_18723489}} | {{ABSTRACT_PUBMED_18723489}} | ||
==About this Structure== | ==About this Structure== | ||
- | [[3c7p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C7P OCA]. | + | [[3c7p]] is a 1 chain structure of [[Carbonic anhydrase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C7P OCA]. |
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+ | ==See Also== | ||
+ | *[[Carbonic anhydrase|Carbonic anhydrase]] | ||
==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018723489</ref><ref group="xtra">PMID:017181151</ref><references group="xtra"/> |
[[Category: Carbonate dehydratase]] | [[Category: Carbonate dehydratase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Fiore, A Di.]] | [[Category: Fiore, A Di.]] | ||
[[Category: Simone, G De.]] | [[Category: Simone, G De.]] | ||
- | [[Category: Acetylation]] | ||
- | [[Category: Cytoplasm]] | ||
[[Category: Disease mutation]] | [[Category: Disease mutation]] | ||
[[Category: Lyase]] | [[Category: Lyase]] | ||
[[Category: Metal-binding]] | [[Category: Metal-binding]] | ||
- | [[Category: Polymorphism]] | ||
[[Category: Protein-inhibitor complex]] | [[Category: Protein-inhibitor complex]] | ||
- | [[Category: Zinc]] |
Revision as of 21:44, 26 July 2012
Contents |
Crystal structure of human carbonic anhydrase II in complex with STX237
Template:ABSTRACT PUBMED 18723489
About this Structure
3c7p is a 1 chain structure of Carbonic anhydrase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Woo LW, Fischer DS, Sharland CM, Trusselle M, Foster PA, Chander SK, Di Fiore A, Supuran CT, De Simone G, Purohit A, Reed MJ, Potter BV. Anticancer steroid sulfatase inhibitors: synthesis of a potent fluorinated second-generation agent, in vitro and in vivo activities, molecular modeling, and protein crystallography. Mol Cancer Ther. 2008 Aug;7(8):2435-44. PMID:18723489 doi:7/8/2435
- Leese MP, Leblond B, Smith A, Newman SP, Di Fiore A, De Simone G, Supuran CT, Purohit A, Reed MJ, Potter BV. 2-substituted estradiol bis-sulfamates, multitargeted antitumor agents: synthesis, in vitro SAR, protein crystallography, and in vivo activity. J Med Chem. 2006 Dec 28;49(26):7683-96. PMID:17181151 doi:10.1021/jm060705x