1z3n
From Proteopedia
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===Human aldose reductase in complex with NADP+ and the inhibitor lidorestat at 1.04 angstrom=== | ===Human aldose reductase in complex with NADP+ and the inhibitor lidorestat at 1.04 angstrom=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[1z3n]] is a 1 chain structure of [[Aldose Reductase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z3N OCA]. | |
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| + | ==See Also== | ||
| + | *[[Aldose Reductase|Aldose Reductase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:015857120</ref><references group="xtra"/> |
[[Category: Aldehyde reductase]] | [[Category: Aldehyde reductase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Nadp+]] | [[Category: Nadp+]] | ||
[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
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Revision as of 22:14, 26 July 2012
Contents |
Human aldose reductase in complex with NADP+ and the inhibitor lidorestat at 1.04 angstrom
Template:ABSTRACT PUBMED 15857120
About this Structure
1z3n is a 1 chain structure of Aldose Reductase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Van Zandt MC, Jones ML, Gunn DE, Geraci LS, Jones JH, Sawicki DR, Sredy J, Jacot JL, Dicioccio AT, Petrova T, Mitschler A, Podjarny AD. Discovery of 3-[(4,5,7-trifluorobenzothiazol-2-yl)methyl]indole-N-acetic acid (lidorestat) and congeners as highly potent and selective inhibitors of aldose reductase for treatment of chronic diabetic complications. J Med Chem. 2005 May 5;48(9):3141-52. PMID:15857120 doi:10.1021/jm0492094
