1uk1
From Proteopedia
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===Crystal structure of human poly(ADP-ribose) polymerase complexed with a potent inhibitor=== | ===Crystal structure of human poly(ADP-ribose) polymerase complexed with a potent inhibitor=== | ||
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{{ABSTRACT_PUBMED_15293985}} | {{ABSTRACT_PUBMED_15293985}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1uk1]] is a 2 chain structure of [[Poly (ADP-ribose) polymerase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UK1 OCA]. | |
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| + | ==See Also== | ||
| + | *[[Poly (ADP-ribose) polymerase|Poly (ADP-ribose) polymerase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:015293985</ref><ref group="xtra">PMID:015690493</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Kinoshita, T.]] | [[Category: Kinoshita, T.]] | ||
[[Category: Protein-inhibitor complex]] | [[Category: Protein-inhibitor complex]] | ||
| - | + | [[Category: Transferase]] | |
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Revision as of 22:26, 26 July 2012
Contents |
Crystal structure of human poly(ADP-ribose) polymerase complexed with a potent inhibitor
Template:ABSTRACT PUBMED 15293985
About this Structure
1uk1 is a 2 chain structure of Poly (ADP-ribose) polymerase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Hattori K, Kido Y, Yamamoto H, Ishida J, Kamijo K, Murano K, Ohkubo M, Kinoshita T, Iwashita A, Mihara K, Yamazaki S, Matsuoka N, Teramura Y, Miyake H. Rational approaches to discovery of orally active and brain-penetrable quinazolinone inhibitors of poly(ADP-ribose)polymerase. J Med Chem. 2004 Aug 12;47(17):4151-4. PMID:15293985 doi:10.1021/jm0499256
- Pang YP. Three-dimensional model of a substrate-bound SARS chymotrypsin-like cysteine proteinase predicted by multiple molecular dynamics simulations: catalytic efficiency regulated by substrate binding. Proteins. 2004 Dec 1;57(4):747-57. PMID:15690493 doi:10.1002/prot.20249
