3lj3
From Proteopedia
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[[Image:3lj3.png|left|200px]] | [[Image:3lj3.png|left|200px]] | ||
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{{STRUCTURE_3lj3| PDB=3lj3 | SCENE= }} | {{STRUCTURE_3lj3| PDB=3lj3 | SCENE= }} | ||
===PI3-kinase-gamma with a pyrrolopyridine-benzofuran inhibitor=== | ===PI3-kinase-gamma with a pyrrolopyridine-benzofuran inhibitor=== | ||
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==See Also== | ==See Also== | ||
| - | *[[Phosphoinositide 3-Kinases]] | + | *[[Phosphoinositide 3-Kinases|Phosphoinositide 3-Kinases]] |
==Reference== | ==Reference== | ||
Revision as of 22:26, 26 July 2012
Contents |
PI3-kinase-gamma with a pyrrolopyridine-benzofuran inhibitor
Template:ABSTRACT PUBMED 20188552
About this Structure
3lj3 is a 1 chain structure of Phosphoinositide 3-Kinases with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Tsou HR, MacEwan G, Birnberg G, Grosu G, Bursavich MG, Bard J, Brooijmans N, Toral-Barza L, Hollander I, Mansour TS, Ayral-Kaloustian S, Yu K. Discovery and optimization of 2-(4-substituted-pyrrolo[2,3-b]pyridin-3-yl)methylene-4-hydroxybenzofuran- 3(2H)-ones as potent and selective ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR). Bioorg Med Chem Lett. 2010 Apr 1;20(7):2321-5. Epub 2010 Feb 2. PMID:20188552 doi:10.1016/j.bmcl.2010.01.135
