3c09
From Proteopedia
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[[Image:3c09.png|left|200px]] | [[Image:3c09.png|left|200px]] | ||
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{{STRUCTURE_3c09| PDB=3c09 | SCENE= }} | {{STRUCTURE_3c09| PDB=3c09 | SCENE= }} | ||
===Crystal structure the Fab fragment of matuzumab (Fab72000) in complex with domain III of the extracellular region of EGFR=== | ===Crystal structure the Fab fragment of matuzumab (Fab72000) in complex with domain III of the extracellular region of EGFR=== | ||
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{{ABSTRACT_PUBMED_18394559}} | {{ABSTRACT_PUBMED_18394559}} | ||
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==See Also== | ==See Also== | ||
| - | *[[Epidermal Growth Factor Receptor]] | + | *[[Epidermal Growth Factor Receptor|Epidermal Growth Factor Receptor]] |
| - | *[[Monoclonal Antibody]] | + | *[[Monoclonal Antibody|Monoclonal Antibody]] |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018394559</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Homo sapiens, mus musculus]] | [[Category: Homo sapiens, mus musculus]] | ||
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[[Category: Antitumor]] | [[Category: Antitumor]] | ||
[[Category: Cell surface receptor]] | [[Category: Cell surface receptor]] | ||
| - | [[Category: Drug immune system | + | [[Category: Drug immune system-transferase complex]] |
[[Category: Fab fragment]] | [[Category: Fab fragment]] | ||
[[Category: Glycoprotein]] | [[Category: Glycoprotein]] | ||
| + | [[Category: Immune system-transferase complex]] | ||
Revision as of 22:34, 26 July 2012
Contents |
Crystal structure the Fab fragment of matuzumab (Fab72000) in complex with domain III of the extracellular region of EGFR
Template:ABSTRACT PUBMED 18394559
About this Structure
3c09 is a 6 chain structure of Epidermal Growth Factor Receptor and Monoclonal Antibody with sequence from Homo sapiens and Homo sapiens, mus musculus. Full crystallographic information is available from OCA.
See Also
Reference
- Schmiedel J, Blaukat A, Li S, Knochel T, Ferguson KM. Matuzumab binding to EGFR prevents the conformational rearrangement required for dimerization. Cancer Cell. 2008 Apr;13(4):365-73. PMID:18394559 doi:10.1016/j.ccr.2008.02.019
Categories: Homo sapiens | Homo sapiens, mus musculus | Receptor protein-tyrosine kinase | Ferguson, K M. | Knoechel, T. | Schmiedel, J. | Antibody complex | Antigen | Antitumor | Cell surface receptor | Drug immune system-transferase complex | Fab fragment | Glycoprotein | Immune system-transferase complex
