2who
From Proteopedia
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{{STRUCTURE_2who| PDB=2who | SCENE= }} | {{STRUCTURE_2who| PDB=2who | SCENE= }} | ||
===CRYSTAL STRUCTURE OF HEPATITIS C VIRUS NS5B POLYMERASE FROM 1B GENOTYPE IN COMPLEX WITH A NON-NUCLEOSIDE INHIBITOR=== | ===CRYSTAL STRUCTURE OF HEPATITIS C VIRUS NS5B POLYMERASE FROM 1B GENOTYPE IN COMPLEX WITH A NON-NUCLEOSIDE INHIBITOR=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[2who]] is a 2 chain structure of [[RNA polymerase]] with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WHO OCA]. | |
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| + | ==See Also== | ||
| + | *[[RNA polymerase|RNA polymerase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019877603</ref><references group="xtra"/> |
[[Category: Hepatitis c virus]] | [[Category: Hepatitis c virus]] | ||
[[Category: RNA-directed RNA polymerase]] | [[Category: RNA-directed RNA polymerase]] | ||
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[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
[[Category: Viral protein]] | [[Category: Viral protein]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 11 22:48:11 2009'' | ||
Revision as of 22:35, 26 July 2012
Contents |
CRYSTAL STRUCTURE OF HEPATITIS C VIRUS NS5B POLYMERASE FROM 1B GENOTYPE IN COMPLEX WITH A NON-NUCLEOSIDE INHIBITOR
Template:ABSTRACT PUBMED 19877603
About this Structure
2who is a 2 chain structure of RNA polymerase with sequence from Hepatitis c virus. Full crystallographic information is available from OCA.
See Also
Reference
- Ontoria JM, Rydberg EH, Di Marco S, Tomei L, Attenni B, Malancona S, Martin Hernando JI, Gennari N, Koch U, Narjes F, Rowley M, Summa V, Carroll SS, Olsen DB, De Francesco R, Altamura S, Migliaccio G, Carfi A. Identification and Biological Evaluation of a Series of 1H-Benzo[de]isoquinoline-1,3(2H)-diones as Hepatitis C Virus NS5B Polymerase Inhibitors (double dagger). J Med Chem. 2009 Aug 27;52(16):5217-27. PMID:19877603 doi:10.1021/jm900517t
Categories: Hepatitis c virus | RNA-directed RNA polymerase | Marco, S Di. | Allosteric inhibitor | Atp-binding | Endoplasmic reticulum | Envelope protein | Genotype 1b | Hcv | Helicase | Hydrolase | Membrane | Metal-binding | Nni | Non nucleoside inhibitor | Ns5b | Nucleotide-binding | Polymerase | Rna replication | Rna-binding | Rna-dependent rna polymerase | Rna-directed rna polymerase | Transferase | Transmembrane | Viral protein
