3l0v

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Revision as of 23:18, 26 July 2012

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Template:STRUCTURE 3l0v

Contents 1 Crystal structure of catalytic domain of TACE with the first hydantoin inhibitor occupying the S1' pocket 2 About this Structure 3 See Also 4 Reference

Crystal structure of catalytic domain of TACE with the first hydantoin inhibitor occupying the S1' pocket

Template:ABSTRACT PUBMED 20172725

About this Structure

3l0v is a 2 chain structure of A Disintegrin And Metalloproteinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• A Disintegrin And Metalloproteinase

Reference

• Yu W, Guo Z, Orth P, Madison V, Chen L, Dai C, Feltz RJ, Girijavallabhan VM, Kim SH, Kozlowski JA, Lavey BJ, Li D, Lundell D, Niu X, Piwinski JJ, Popovici-Muller J, Rizvi R, Rosner KE, Shankar BB, Shih NY, Siddiqui MA, Sun J, Tong L, Umland S, Wong MK, Yang DY, Zhou G. Discovery and SAR of hydantoin TACE inhibitors. Bioorg Med Chem Lett. 2010 Mar 15;20(6):1877-80. Epub 2010 Feb 4. PMID:20172725 doi:10.1016/j.bmcl.2010.01.148