1qj7
From Proteopedia
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[[Image:1qj7.png|left|200px]] | [[Image:1qj7.png|left|200px]] | ||
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{{STRUCTURE_1qj7| PDB=1qj7 | SCENE= }} | {{STRUCTURE_1qj7| PDB=1qj7 | SCENE= }} | ||
===NOVEL COVALENT ACTIVE SITE THROMBIN INHIBITORS=== | ===NOVEL COVALENT ACTIVE SITE THROMBIN INHIBITORS=== | ||
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{{ABSTRACT_PUBMED_10387040}} | {{ABSTRACT_PUBMED_10387040}} | ||
==About this Structure== | ==About this Structure== | ||
- | [[1qj7]] is a 3 chain structure of [[Hirudin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QJ7 OCA]. | + | [[1qj7]] is a 3 chain structure of [[Hirudin]] and [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QJ7 OCA]. |
==See Also== | ==See Also== | ||
- | *[[Hirudin]] | + | *[[Hirudin|Hirudin]] |
+ | *[[Thrombin|Thrombin]] | ||
==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:010387040</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Thrombin]] | [[Category: Thrombin]] | ||
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[[Category: Wonacott, A.]] | [[Category: Wonacott, A.]] | ||
[[Category: Blood coagulation]] | [[Category: Blood coagulation]] | ||
- | [[Category: Hydrolase | + | [[Category: Blood coagulation-inhibitor complex]] |
+ | [[Category: Hydrolase- hydrolase inhibitor complex]] | ||
+ | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
+ | [[Category: Protease-inhibitor complex]] | ||
[[Category: Proteinase]] | [[Category: Proteinase]] | ||
[[Category: Trypsin like proteinase]] | [[Category: Trypsin like proteinase]] |
Revision as of 23:21, 26 July 2012
Contents |
NOVEL COVALENT ACTIVE SITE THROMBIN INHIBITORS
Template:ABSTRACT PUBMED 10387040
About this Structure
1qj7 is a 3 chain structure of Hirudin and Thrombin with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Jhoti H, Cleasby A, Reid S, Thomas PJ, Weir M, Wonacott A. Crystal structures of thrombin complexed to a novel series of synthetic inhibitors containing a 5,5-trans-lactone template. Biochemistry. 1999 Jun 22;38(25):7969-77. PMID:10387040 doi:http://dx.doi.org/10.1021/bi9830359
Categories: Homo sapiens | Thrombin | Cleasby, A. | Jhoti, H. | Reid, S. | Thomas, P. | Weir, M. | Wonacott, A. | Blood coagulation | Blood coagulation-inhibitor complex | Hydrolase- hydrolase inhibitor complex | Hydrolase-hydrolase inhibitor complex | Protease-inhibitor complex | Proteinase | Trypsin like proteinase