3msl
From Proteopedia
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[[Image:3msl.png|left|200px]] | [[Image:3msl.png|left|200px]] | ||
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{{STRUCTURE_3msl| PDB=3msl | SCENE= }} | {{STRUCTURE_3msl| PDB=3msl | SCENE= }} | ||
===Fragment Based Discovery and Optimisation of BACE-1 Inhibitors=== | ===Fragment Based Discovery and Optimisation of BACE-1 Inhibitors=== | ||
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{{ABSTRACT_PUBMED_20656487}} | {{ABSTRACT_PUBMED_20656487}} | ||
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==See Also== | ==See Also== | ||
| - | *[[Beta secretase]] | + | *[[Beta secretase|Beta secretase]] |
==Reference== | ==Reference== | ||
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[[Category: Madden, J.]] | [[Category: Madden, J.]] | ||
[[Category: Smith, M.]] | [[Category: Smith, M.]] | ||
| + | [[Category: Alzheimer's disease]] | ||
| + | [[Category: Amyloid precursor protein secretase]] | ||
| + | [[Category: Aspartic endopeptidase]] | ||
| + | [[Category: Aspartic protease]] | ||
| + | [[Category: Aspartyl protease]] | ||
| + | [[Category: Base]] | ||
| + | [[Category: Beta-secretase]] | ||
| + | [[Category: Fluorescence polarisation]] | ||
| + | [[Category: Fragment-based drug design]] | ||
| + | [[Category: Glycoprotein]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
| + | [[Category: Memapsin 2]] | ||
| + | [[Category: Protease]] | ||
| + | [[Category: Transmembrane]] | ||
| + | [[Category: Zymogen]] | ||
Revision as of 00:08, 27 July 2012
Contents |
Fragment Based Discovery and Optimisation of BACE-1 Inhibitors
Template:ABSTRACT PUBMED 20656487
About this Structure
3msl is a 1 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Madden J, Dod JR, Godemann R, Kraemer J, Smith M, Biniszkiewicz M, Hallett DJ, Barker J, Dyekjaer JD, Hesterkamp T. Fragment-based discovery and optimization of BACE1 inhibitors. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5329-33. Epub 2010 Jun 27. PMID:20656487 doi:10.1016/j.bmcl.2010.06.089
Categories: Homo sapiens | Memapsin 2 | Barker, J. | Madden, J. | Smith, M. | Alzheimer's disease | Amyloid precursor protein secretase | Aspartic endopeptidase | Aspartic protease | Aspartyl protease | Base | Beta-secretase | Fluorescence polarisation | Fragment-based drug design | Glycoprotein | Hydrolase | Hydrolase-hydrolase inhibitor complex | Protease | Transmembrane | Zymogen
