1z8i
From Proteopedia
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{{STRUCTURE_1z8i| PDB=1z8i | SCENE= }} | {{STRUCTURE_1z8i| PDB=1z8i | SCENE= }} | ||
===Crystal structure of the thrombin mutant G193A bound to PPACK=== | ===Crystal structure of the thrombin mutant G193A bound to PPACK=== | ||
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{{ABSTRACT_PUBMED_15890651}} | {{ABSTRACT_PUBMED_15890651}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Dysprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hyperprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hypoprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1z8i]] is a 2 chain structure of [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z8I OCA]. | |
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| + | ==See Also== | ||
| + | *[[Thrombin|Thrombin]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:015890651</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Thrombin]] | [[Category: Thrombin]] | ||
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[[Category: Mathews, F S.]] | [[Category: Mathews, F S.]] | ||
[[Category: Pineda, A O.]] | [[Category: Pineda, A O.]] | ||
| + | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
[[Category: Oxyanion hole]] | [[Category: Oxyanion hole]] | ||
[[Category: Serine protease]] | [[Category: Serine protease]] | ||
| - | [[Category: Thrombin]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 17:23:29 2009'' | ||
Revision as of 00:14, 27 July 2012
Contents |
Crystal structure of the thrombin mutant G193A bound to PPACK
Template:ABSTRACT PUBMED 15890651
About this Structure
1z8i is a 2 chain structure of Thrombin with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Bobofchak KM, Pineda AO, Mathews FS, Di Cera E. Energetic and structural consequences of perturbing Gly-193 in the oxyanion hole of serine proteases. J Biol Chem. 2005 Jul 8;280(27):25644-50. Epub 2005 May 12. PMID:15890651 doi:http://dx.doi.org/10.1074/jbc.M503499200
