3dtc
From Proteopedia
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===Crystal structure of mixed-lineage kinase MLK1 complexed with compound 16=== | ===Crystal structure of mixed-lineage kinase MLK1 complexed with compound 16=== | ||
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Revision as of 00:16, 27 July 2012
Contents |
Crystal structure of mixed-lineage kinase MLK1 complexed with compound 16
Template:ABSTRACT PUBMED 18714982
About this Structure
3dtc is a 1 chain structure of Mitogen-activated protein kinase kinase kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Hudkins RL, Diebold JL, Tao M, Josef KA, Park CH, Angeles TS, Aimone LD, Husten J, Ator MA, Meyer SL, Holskin BP, Durkin JT, Fedorov AA, Fedorov EV, Almo SC, Mathiasen JR, Bozyczko-Coyne D, Saporito MS, Scott RW, Mallamo JP. Mixed-lineage kinase 1 and mixed-lineage kinase 3 subtype-selective dihydronaphthyl[3,4-a]pyrrolo[3,4-c]carbazole-5-ones: optimization, mixed-lineage kinase 1 crystallography, and oral in vivo activity in 1-methyl-4-phenyltetrahydropyridine models. J Med Chem. 2008 Sep 25;51(18):5680-9. Epub 2008 Aug 21. PMID:18714982 doi:10.1021/jm8005838
Categories: Homo sapiens | Mitogen-activated protein kinase kinase kinase | Almo, S C. | Fedorov, A A. | Fedorov, E V. | Hudkins, R L. | Meyer, S L. | Atp-binding | Kinase | Mixed-lineage kinase | Mlk family | Mlk1 and mlk3 subtype selective inhibitor | Nucleotide-binding | Phosphoprotein | Serine/threonine-protein kinase | Sh3 domain | Transferase
