3m2w

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[[Image:3m2w.png|left|200px]]
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{{STRUCTURE_3m2w| PDB=3m2w | SCENE= }}
{{STRUCTURE_3m2w| PDB=3m2w | SCENE= }}
===Crystal structure of MAPKAK kinase 2 (MK2) complexed with a spiroazetidine-tetracyclic ATP site inhibitor===
===Crystal structure of MAPKAK kinase 2 (MK2) complexed with a spiroazetidine-tetracyclic ATP site inhibitor===
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{{ABSTRACT_PUBMED_20591669}}
{{ABSTRACT_PUBMED_20591669}}
==About this Structure==
==About this Structure==
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3M2W is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M2W OCA].
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[[3m2w]] is a 1 chain structure of [[Mitogen-activated protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M2W OCA].
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==See Also==
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*[[Mitogen-activated protein kinase|Mitogen-activated protein kinase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:20591669</ref><references group="xtra"/>
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<ref group="xtra">PMID:020591669</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Spiroazetidine-tetracycle]]
[[Category: Spiroazetidine-tetracycle]]
[[Category: Transferase]]
[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 28 12:37:21 2010''
 

Revision as of 00:20, 27 July 2012

Image:3m2w.png

Template:STRUCTURE 3m2w

Contents

Crystal structure of MAPKAK kinase 2 (MK2) complexed with a spiroazetidine-tetracyclic ATP site inhibitor

Template:ABSTRACT PUBMED 20591669

About this Structure

3m2w is a 1 chain structure of Mitogen-activated protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Revesz L, Schlapbach A, Aichholz R, Dawson J, Feifel R, Hawtin S, Littlewood-Evans A, Koch G, Kroemer M, Mobitz H, Scheufler C, Velcicky J, Huppertz C. In vivo and in vitro SAR of tetracyclic MAPKAP-K2 (MK2) inhibitors. Part II. Bioorg Med Chem Lett. 2010 Aug 1;20(15):4719-23. Epub 2010 Apr 11. PMID:20591669 doi:10.1016/j.bmcl.2010.04.023

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