1fnz
From Proteopedia
(New page: 200px<br /><applet load="1fnz" size="450" color="white" frame="true" align="right" spinBox="true" caption="1fnz, resolution 2.05Å" /> '''A BARK LECTIN FROM R...) |
|||
| Line 1: | Line 1: | ||
| - | [[Image:1fnz.gif|left|200px]]<br /><applet load="1fnz" size=" | + | [[Image:1fnz.gif|left|200px]]<br /><applet load="1fnz" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1fnz, resolution 2.05Å" /> | caption="1fnz, resolution 2.05Å" /> | ||
'''A BARK LECTIN FROM ROBINIA PSEUDOACACIA IN COMPLEX WITH N-ACETYLGALACTOSAMINE.'''<br /> | '''A BARK LECTIN FROM ROBINIA PSEUDOACACIA IN COMPLEX WITH N-ACETYLGALACTOSAMINE.'''<br /> | ||
==Overview== | ==Overview== | ||
| - | The structure of the bark lectin RPbAI (isoform A4) from Robinia | + | The structure of the bark lectin RPbAI (isoform A4) from Robinia pseudoacacia has been determined by protein crystallography both in the free form and complexed with N-acetylgalactosamine. The free form is refined at 1.80 A resolution to an R-factor of 18.9% whereas the complexed structure has an R-factor of 19.7% at 2.05 A resolution. Both structures are compared to each other and to other available legume lectin structures. The polypeptide chains of the two structures exhibit the characteristic legume lectin tertiary fold. The quaternary structure resembles that of the Phaseolus vulgaris lectin, the soybean agglutinin, and the Dolichos biflorus lectin, but displays some unique features leading to the extreme stability of this lectin. |
==About this Structure== | ==About this Structure== | ||
| - | 1FNZ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Robinia_pseudoacacia Robinia pseudoacacia] with A2G and CA as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http:// | + | 1FNZ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Robinia_pseudoacacia Robinia pseudoacacia] with <scene name='pdbligand=A2G:'>A2G</scene> and <scene name='pdbligand=CA:'>CA</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FNZ OCA]. |
==Reference== | ==Reference== | ||
| Line 14: | Line 14: | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Barre, A.]] | [[Category: Barre, A.]] | ||
| - | [[Category: Damme, E | + | [[Category: Damme, E J.Van.]] |
| - | [[Category: Peumans, W | + | [[Category: Peumans, W J.]] |
[[Category: Rabijns, A.]] | [[Category: Rabijns, A.]] | ||
| - | [[Category: Ranter, C | + | [[Category: Ranter, C J.De.]] |
[[Category: Rouge, P.]] | [[Category: Rouge, P.]] | ||
[[Category: Verboven, C.]] | [[Category: Verboven, C.]] | ||
| Line 24: | Line 24: | ||
[[Category: jelly roll]] | [[Category: jelly roll]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:40:45 2008'' |
Revision as of 10:40, 21 February 2008
|
A BARK LECTIN FROM ROBINIA PSEUDOACACIA IN COMPLEX WITH N-ACETYLGALACTOSAMINE.
Overview
The structure of the bark lectin RPbAI (isoform A4) from Robinia pseudoacacia has been determined by protein crystallography both in the free form and complexed with N-acetylgalactosamine. The free form is refined at 1.80 A resolution to an R-factor of 18.9% whereas the complexed structure has an R-factor of 19.7% at 2.05 A resolution. Both structures are compared to each other and to other available legume lectin structures. The polypeptide chains of the two structures exhibit the characteristic legume lectin tertiary fold. The quaternary structure resembles that of the Phaseolus vulgaris lectin, the soybean agglutinin, and the Dolichos biflorus lectin, but displays some unique features leading to the extreme stability of this lectin.
About this Structure
1FNZ is a Single protein structure of sequence from Robinia pseudoacacia with and as ligands. Full crystallographic information is available from OCA.
Reference
Structure of a legume lectin from the bark of Robinia pseudoacacia and its complex with N-acetylgalactosamine., Rabijns A, Verboven C, Rouge P, Barre A, Van Damme EJ, Peumans WJ, De Ranter CJ, Proteins. 2001 Sep 1;44(4):470-8. PMID:11484224
Page seeded by OCA on Thu Feb 21 12:40:45 2008
