1fo5
From Proteopedia
(New page: 200px<br /><applet load="1fo5" size="450" color="white" frame="true" align="right" spinBox="true" caption="1fo5" /> '''SOLUTION STRUCTURE OF REDUCED MJ0307'''<br /...) |
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| - | [[Image:1fo5.gif|left|200px]]<br /><applet load="1fo5" size=" | + | [[Image:1fo5.gif|left|200px]]<br /><applet load="1fo5" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1fo5" /> | caption="1fo5" /> | ||
'''SOLUTION STRUCTURE OF REDUCED MJ0307'''<br /> | '''SOLUTION STRUCTURE OF REDUCED MJ0307'''<br /> | ||
==Overview== | ==Overview== | ||
| - | The solution structure of the protein disulfide oxidoreductase Mj0307 in | + | The solution structure of the protein disulfide oxidoreductase Mj0307 in the reduced form has been solved by nuclear magnetic resonance. The secondary and tertiary structure of this protein from the archaebacterium Methanococcus jannaschii is similar to the structures that have been solved for the glutaredoxin proteins from Escherichia coli, although Mj0307 also shows features that are characteristic of thioredoxin proteins. Some aspects of Mj0307's unique behavior can be explained by comparing structure-based sequence alignments with mesophilic bacterial and eukaryotic glutaredoxin and thioredoxin proteins. It is proposed that Mj0307, and similar archaebacterial proteins, may be most closely related to the mesophilic bacterial NrdH proteins. Together these proteins may form a unique subgroup within the family of protein disulfide oxidoreductases. |
==About this Structure== | ==About this Structure== | ||
| - | 1FO5 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http:// | + | 1FO5 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FO5 OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Methanocaldococcus jannaschii]] | [[Category: Methanocaldococcus jannaschii]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| - | [[Category: BSGC, Berkeley | + | [[Category: BSGC, Berkeley Structural Genomics Center.]] |
| - | [[Category: Batchelder, A | + | [[Category: Batchelder, A M.]] |
| - | [[Category: Cave, J | + | [[Category: Cave, J W.]] |
| - | [[Category: Cho, H | + | [[Category: Cho, H S.]] |
[[Category: Kim, R.]] | [[Category: Kim, R.]] | ||
| - | [[Category: Wemmer, D | + | [[Category: Wemmer, D E.]] |
[[Category: Yokota, H.]] | [[Category: Yokota, H.]] | ||
[[Category: berkeley structural genomics center]] | [[Category: berkeley structural genomics center]] | ||
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[[Category: thioredoxin fold]] | [[Category: thioredoxin fold]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:40:50 2008'' |
Revision as of 10:40, 21 February 2008
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SOLUTION STRUCTURE OF REDUCED MJ0307
Overview
The solution structure of the protein disulfide oxidoreductase Mj0307 in the reduced form has been solved by nuclear magnetic resonance. The secondary and tertiary structure of this protein from the archaebacterium Methanococcus jannaschii is similar to the structures that have been solved for the glutaredoxin proteins from Escherichia coli, although Mj0307 also shows features that are characteristic of thioredoxin proteins. Some aspects of Mj0307's unique behavior can be explained by comparing structure-based sequence alignments with mesophilic bacterial and eukaryotic glutaredoxin and thioredoxin proteins. It is proposed that Mj0307, and similar archaebacterial proteins, may be most closely related to the mesophilic bacterial NrdH proteins. Together these proteins may form a unique subgroup within the family of protein disulfide oxidoreductases.
About this Structure
1FO5 is a Single protein structure of sequence from Methanocaldococcus jannaschii. Full crystallographic information is available from OCA.
Reference
Solution nuclear magnetic resonance structure of a protein disulfide oxidoreductase from Methanococcus jannaschii., Cave JW, Cho HS, Batchelder AM, Yokota H, Kim R, Wemmer DE, Protein Sci. 2001 Feb;10(2):384-96. PMID:11266624
Page seeded by OCA on Thu Feb 21 12:40:50 2008
Categories: Methanocaldococcus jannaschii | Single protein | BSGC, Berkeley Structural Genomics Center. | Batchelder, A M. | Cave, J W. | Cho, H S. | Kim, R. | Wemmer, D E. | Yokota, H. | Berkeley structural genomics center | Bsgc structure funded by nih | Disulfide oxidoreductase | Protein structure initiative | Psi | Structural genomics | Thioredoxin fold
