This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1jug
From Proteopedia
(New page: 200px<br /> <applet load="1jug" size="450" color="white" frame="true" align="right" spinBox="true" caption="1jug, resolution 1.9Å" /> '''LYSOZYME FROM ECHIDN...) |
|||
| Line 8: | Line 8: | ||
==About this Structure== | ==About this Structure== | ||
| - | 1JUG is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Tachyglossus_aculeatus Tachyglossus aculeatus]] with CA as [[http://en.wikipedia.org/wiki/ligand ligand]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1JUG OCA]]. | + | 1JUG is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Tachyglossus_aculeatus Tachyglossus aculeatus]] with CA as [[http://en.wikipedia.org/wiki/ligand ligand]]. Active as [[http://en.wikipedia.org/wiki/Lysozyme Lysozyme]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17]]. Structure known Active Site: CAB. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1JUG OCA]]. |
==Reference== | ==Reference== | ||
Structure of the calcium-binding echidna milk lysozyme at 1.9 A resolution., Guss JM, Messer M, Costello M, Hardy K, Kumar V, Acta Crystallogr D Biol Crystallogr. 1997 Jul 1;53(Pt 4):355-63. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15299900 15299900] | Structure of the calcium-binding echidna milk lysozyme at 1.9 A resolution., Guss JM, Messer M, Costello M, Hardy K, Kumar V, Acta Crystallogr D Biol Crystallogr. 1997 Jul 1;53(Pt 4):355-63. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15299900 15299900] | ||
| + | [[Category: Lysozyme]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Tachyglossus aculeatus]] | [[Category: Tachyglossus aculeatus]] | ||
| Line 19: | Line 20: | ||
[[Category: lysozyme]] | [[Category: lysozyme]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 14:03:59 2007'' |
Revision as of 11:59, 30 October 2007
|
LYSOZYME FROM ECHIDNA MILK (TACHYGLOSSUS ACULEATUS)
Overview
A lysozyme isolated from the milk of a monotreme, the echidna, Tachyglossus aculeatus multiaculeatus, has been crystallized (space group, P2(1), with unit-cell dimensions a = 37.1, b = 42.0, c = 38.1 A, beta = 91, degrees and Z = 2) and the structure refined to an R value of 0.167 for, all measured data in the resolution range 7.0-1.9 A. It had previously, been inferred from sequence homology with alpha-lactalbumins that echidna, milk lysozyme (EML) would bind one calcium ion per molecule. This has been, confirmed in the present study in which the largest peak in a difference, Fourier synthesis is associated with a calcium ion. The calcium binding, site of EML is very similar to that observed in baboon and human, alpha-lactalbumins, and in a human lysozyme engineered to contain a, ... [(full description)]
About this Structure
1JUG is a [Single protein] structure of sequence from [Tachyglossus aculeatus] with CA as [ligand]. Active as [Lysozyme], with EC number [3.2.1.17]. Structure known Active Site: CAB. Full crystallographic information is available from [OCA].
Reference
Structure of the calcium-binding echidna milk lysozyme at 1.9 A resolution., Guss JM, Messer M, Costello M, Hardy K, Kumar V, Acta Crystallogr D Biol Crystallogr. 1997 Jul 1;53(Pt 4):355-63. PMID:15299900
Page seeded by OCA on Tue Oct 30 14:03:59 2007
