1jug
From Proteopedia
(New page: 200px<br /> <applet load="1jug" size="450" color="white" frame="true" align="right" spinBox="true" caption="1jug, resolution 1.9Å" /> '''LYSOZYME FROM ECHIDN...) |
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==About this Structure== | ==About this Structure== | ||
| - | 1JUG is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Tachyglossus_aculeatus Tachyglossus aculeatus]] with CA as [[http://en.wikipedia.org/wiki/ligand ligand]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1JUG OCA]]. | + | 1JUG is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Tachyglossus_aculeatus Tachyglossus aculeatus]] with CA as [[http://en.wikipedia.org/wiki/ligand ligand]]. Active as [[http://en.wikipedia.org/wiki/Lysozyme Lysozyme]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17]]. Structure known Active Site: CAB. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1JUG OCA]]. |
==Reference== | ==Reference== | ||
Structure of the calcium-binding echidna milk lysozyme at 1.9 A resolution., Guss JM, Messer M, Costello M, Hardy K, Kumar V, Acta Crystallogr D Biol Crystallogr. 1997 Jul 1;53(Pt 4):355-63. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15299900 15299900] | Structure of the calcium-binding echidna milk lysozyme at 1.9 A resolution., Guss JM, Messer M, Costello M, Hardy K, Kumar V, Acta Crystallogr D Biol Crystallogr. 1997 Jul 1;53(Pt 4):355-63. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15299900 15299900] | ||
| + | [[Category: Lysozyme]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Tachyglossus aculeatus]] | [[Category: Tachyglossus aculeatus]] | ||
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[[Category: lysozyme]] | [[Category: lysozyme]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 14:03:59 2007'' |
Revision as of 11:59, 30 October 2007
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LYSOZYME FROM ECHIDNA MILK (TACHYGLOSSUS ACULEATUS)
Overview
A lysozyme isolated from the milk of a monotreme, the echidna, Tachyglossus aculeatus multiaculeatus, has been crystallized (space group, P2(1), with unit-cell dimensions a = 37.1, b = 42.0, c = 38.1 A, beta = 91, degrees and Z = 2) and the structure refined to an R value of 0.167 for, all measured data in the resolution range 7.0-1.9 A. It had previously, been inferred from sequence homology with alpha-lactalbumins that echidna, milk lysozyme (EML) would bind one calcium ion per molecule. This has been, confirmed in the present study in which the largest peak in a difference, Fourier synthesis is associated with a calcium ion. The calcium binding, site of EML is very similar to that observed in baboon and human, alpha-lactalbumins, and in a human lysozyme engineered to contain a, ... [(full description)]
About this Structure
1JUG is a [Single protein] structure of sequence from [Tachyglossus aculeatus] with CA as [ligand]. Active as [Lysozyme], with EC number [3.2.1.17]. Structure known Active Site: CAB. Full crystallographic information is available from [OCA].
Reference
Structure of the calcium-binding echidna milk lysozyme at 1.9 A resolution., Guss JM, Messer M, Costello M, Hardy K, Kumar V, Acta Crystallogr D Biol Crystallogr. 1997 Jul 1;53(Pt 4):355-63. PMID:15299900
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