1tl3
From Proteopedia
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[[Image:1tl3.png|left|200px]] | [[Image:1tl3.png|left|200px]] | ||
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{{STRUCTURE_1tl3| PDB=1tl3 | SCENE= }} | {{STRUCTURE_1tl3| PDB=1tl3 | SCENE= }} | ||
===Crystal structure of hiv-1 reverse transcriptase in complex with gw450557=== | ===Crystal structure of hiv-1 reverse transcriptase in complex with gw450557=== | ||
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==See Also== | ==See Also== | ||
- | *[[Reverse transcriptase]] | + | *[[Reverse transcriptase|Reverse transcriptase]] |
==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:015537346</ref><ref group="xtra">PMID:007724588</ref><references group="xtra"/> |
[[Category: Human immunodeficiency virus 1]] | [[Category: Human immunodeficiency virus 1]] | ||
[[Category: RNA-directed DNA polymerase]] | [[Category: RNA-directed DNA polymerase]] |
Revision as of 01:24, 27 July 2012
Contents |
Crystal structure of hiv-1 reverse transcriptase in complex with gw450557
Template:ABSTRACT PUBMED 15537346
About this Structure
1tl3 is a 2 chain structure of Reverse transcriptase with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.
See Also
Reference
- Hopkins AL, Ren J, Milton J, Hazen RJ, Chan JH, Stuart DI, Stammers DK. Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved drug resistance properties. 1. J Med Chem. 2004 Nov 18;47(24):5912-22. PMID:15537346 doi:10.1021/jm040071z
- Weichsel A, Montfort WR, Ciesla J, Maley F. Promotion of purine nucleotide binding to thymidylate synthase by a potent folate analogue inhibitor, 1843U89. Proc Natl Acad Sci U S A. 1995 Apr 11;92(8):3493-7. PMID:7724588