1tl3

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[[Image:1tl3.png|left|200px]]
[[Image:1tl3.png|left|200px]]
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{{STRUCTURE_1tl3| PDB=1tl3 | SCENE= }}
{{STRUCTURE_1tl3| PDB=1tl3 | SCENE= }}
===Crystal structure of hiv-1 reverse transcriptase in complex with gw450557===
===Crystal structure of hiv-1 reverse transcriptase in complex with gw450557===
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{{ABSTRACT_PUBMED_15537346}}
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==See Also==
==See Also==
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*[[Reverse transcriptase]]
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*[[Reverse transcriptase|Reverse transcriptase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:15537346</ref><references group="xtra"/>
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<ref group="xtra">PMID:015537346</ref><ref group="xtra">PMID:007724588</ref><references group="xtra"/>
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
[[Category: RNA-directed DNA polymerase]]
[[Category: RNA-directed DNA polymerase]]

Revision as of 01:24, 27 July 2012

Template:STRUCTURE 1tl3

Contents

Crystal structure of hiv-1 reverse transcriptase in complex with gw450557

Template:ABSTRACT PUBMED 15537346

About this Structure

1tl3 is a 2 chain structure of Reverse transcriptase with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

See Also

Reference

  • Hopkins AL, Ren J, Milton J, Hazen RJ, Chan JH, Stuart DI, Stammers DK. Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved drug resistance properties. 1. J Med Chem. 2004 Nov 18;47(24):5912-22. PMID:15537346 doi:10.1021/jm040071z
  • Weichsel A, Montfort WR, Ciesla J, Maley F. Promotion of purine nucleotide binding to thymidylate synthase by a potent folate analogue inhibitor, 1843U89. Proc Natl Acad Sci U S A. 1995 Apr 11;92(8):3493-7. PMID:7724588

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