3nw5

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[[Image:3nw5.png|left|200px]]
[[Image:3nw5.png|left|200px]]
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{{STRUCTURE_3nw5| PDB=3nw5 | SCENE= }}
{{STRUCTURE_3nw5| PDB=3nw5 | SCENE= }}
===Crystal structure of insulin-like growth factor 1 receptor (IGF-1R-WT) complex with a carbon-linked proline isostere inhibitor (11B)===
===Crystal structure of insulin-like growth factor 1 receptor (IGF-1R-WT) complex with a carbon-linked proline isostere inhibitor (11B)===
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{{ABSTRACT_PUBMED_20675137}}
{{ABSTRACT_PUBMED_20675137}}
==About this Structure==
==About this Structure==
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3NW5 is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NW5 OCA].
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[[3nw5]] is a 1 chain structure of [[Hormone]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NW5 OCA].
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==See Also==
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*[[Hormone|Hormone]]
==Reference==
==Reference==
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<ref group="xtra">PMID:20675137</ref><references group="xtra"/>
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<ref group="xtra">PMID:020675137</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Receptor protein-tyrosine kinase]]
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[[Category: Kinase domain]]
[[Category: Kinase domain]]
[[Category: Transferase]]
[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri Sep 10 13:35:45 2010''
 

Revision as of 01:39, 27 July 2012

Template:STRUCTURE 3nw5

Contents

Crystal structure of insulin-like growth factor 1 receptor (IGF-1R-WT) complex with a carbon-linked proline isostere inhibitor (11B)

Template:ABSTRACT PUBMED 20675137

About this Structure

3nw5 is a 1 chain structure of Hormone with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Sampognaro AJ, Wittman MD, Carboni JM, Chang C, Greer AF, Hurlburt WW, Sack JS, Vyas DM. Proline isosteres in a series of 2,4-disubstituted pyrrolo[1,2-f][1,2,4]triazine inhibitors of IGF-1R kinase and IR kinase. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5027-30. Epub 2010 Jul 15. PMID:20675137 doi:10.1016/j.bmcl.2010.07.045

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