2hmi
From Proteopedia
(Difference between revisions)
m (Protected "2hmi" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
[[Image:2hmi.png|left|200px]] | [[Image:2hmi.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_2hmi", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_2hmi| PDB=2hmi | SCENE= }} | {{STRUCTURE_2hmi| PDB=2hmi | SCENE= }} | ||
===HIV-1 REVERSE TRANSCRIPTASE/FRAGMENT OF FAB 28/DNA COMPLEX=== | ===HIV-1 REVERSE TRANSCRIPTASE/FRAGMENT OF FAB 28/DNA COMPLEX=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_9837729}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 9837729 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_9837729}} | {{ABSTRACT_PUBMED_9837729}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[2hmi]] is a 6 chain structure of [[Reverse transcriptase]] with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1hmi 1hmi]. The September 2002 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Reverse Transcriptase'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2002_9 10.2210/rcsb_pdb/mom_2002_9]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HMI OCA]. | + | [[2hmi]] is a 6 chain structure of [[Monoclonal Antibody]] and [[Reverse transcriptase]] with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1hmi 1hmi]. The September 2002 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Reverse Transcriptase'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2002_9 10.2210/rcsb_pdb/mom_2002_9]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HMI OCA]. |
==See Also== | ==See Also== | ||
| - | *[[Reverse transcriptase]] | + | *[[Monoclonal Antibody|Monoclonal Antibody]] |
| + | *[[Reverse transcriptase|Reverse transcriptase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:009837729</ref><ref group="xtra">PMID:009843431</ref><references group="xtra"/> |
[[Category: Human immunodeficiency virus 1]] | [[Category: Human immunodeficiency virus 1]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| Line 35: | Line 25: | ||
[[Category: Aid]] | [[Category: Aid]] | ||
[[Category: Hiv-1]] | [[Category: Hiv-1]] | ||
| - | [[Category: Immune system | + | [[Category: Immune system-dna complex]] |
[[Category: Polymerase]] | [[Category: Polymerase]] | ||
[[Category: Rt]] | [[Category: Rt]] | ||
Revision as of 01:43, 27 July 2012
Contents |
HIV-1 REVERSE TRANSCRIPTASE/FRAGMENT OF FAB 28/DNA COMPLEX
Template:ABSTRACT PUBMED 9837729
About this Structure
2hmi is a 6 chain structure of Monoclonal Antibody and Reverse transcriptase with sequence from Human immunodeficiency virus 1 and Mus musculus. This structure supersedes the now removed PDB entry 1hmi. The September 2002 RCSB PDB Molecule of the Month feature on Reverse Transcriptase by David S. Goodsell is 10.2210/rcsb_pdb/mom_2002_9. Full crystallographic information is available from OCA.
See Also
Reference
- Ding J, Das K, Hsiou Y, Sarafianos SG, Clark AD Jr, Jacobo-Molina A, Tantillo C, Hughes SH, Arnold E. Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double-stranded DNA template-primer and an antibody Fab fragment at 2.8 A resolution. J Mol Biol. 1998 Dec 11;284(4):1095-111. PMID:9837729 doi:10.1006/jmbi.1998.2208
- Menendez-Arias L. Studies on the effects of truncating alpha-helix E' of p66 human immunodeficiency virus type 1 reverse transcriptase on template-primer binding and fidelity of DNA synthesis. Biochemistry. 1998 Nov 24;37(47):16636-44. PMID:9843431 doi:10.1021/bi981830g
