2puq
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | {{Seed}} | ||
[[Image:2puq.png|left|200px]] | [[Image:2puq.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_2puq", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_2puq| PDB=2puq | SCENE= }} | {{STRUCTURE_2puq| PDB=2puq | SCENE= }} | ||
===Crystal structure of active site inhibited coagulation factor VIIA in complex with soluble tissue factor=== | ===Crystal structure of active site inhibited coagulation factor VIIA in complex with soluble tissue factor=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_17456045}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 17456045 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_17456045}} | {{ABSTRACT_PUBMED_17456045}} | ||
| - | |||
| - | ==Disease== | ||
| - | Known disease associated with this structure: Factor VII deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227500 227500]], Myocardial infarction, decreased susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227500 227500]], Renal tubular dysgenesis OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=106180 106180]], Angiotensin I-converting enzyme, benign serum increase OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=106180 106180]], Alzheimer disease, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=106180 106180]], Microvascular complications of diabetes 3 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=106180 106180]], Myocardial infarction, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=106180 106180]], SARS, progression of OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=106180 106180]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2puq]] is a 4 chain structure of [[Factor VIIa]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2pmm 2pmm]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PUQ OCA]. | |
| + | |||
| + | ==See Also== | ||
| + | *[[Factor VIIa|Factor VIIa]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017456045</ref><references group="xtra"/> |
[[Category: Coagulation factor VIIa]] | [[Category: Coagulation factor VIIa]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| Line 33: | Line 21: | ||
[[Category: Active site inhibitor]] | [[Category: Active site inhibitor]] | ||
[[Category: Blood clotting]] | [[Category: Blood clotting]] | ||
| - | [[Category: | + | [[Category: Hydrolase]] |
| - | + | [[Category: Hydrolase-hydrolase inhibitor complex]] | |
| - | + | ||
Revision as of 01:46, 27 July 2012
Contents |
Crystal structure of active site inhibited coagulation factor VIIA in complex with soluble tissue factor
Template:ABSTRACT PUBMED 17456045
About this Structure
2puq is a 4 chain structure of Factor VIIa with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 2pmm. Full crystallographic information is available from OCA.
See Also
Reference
- Larsen KS, Ostergaard H, Bjelke JR, Olsen OH, Rasmussen HB, Christensen L, Kragelund BB, Stennicke HR. Engineering the substrate and inhibitor specificities of human coagulation Factor VIIa. Biochem J. 2007 Aug 1;405(3):429-38. PMID:17456045 doi:http://dx.doi.org/10.1042/BJ20061901
