1sc7
From Proteopedia
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[[Image:1sc7.png|left|200px]] | [[Image:1sc7.png|left|200px]] | ||
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===Human DNA Topoisomerase I (70 Kda) In Complex With The Indenoisoquinoline MJ-II-38 and Covalent Complex With A 22 Base Pair DNA Duplex=== | ===Human DNA Topoisomerase I (70 Kda) In Complex With The Indenoisoquinoline MJ-II-38 and Covalent Complex With A 22 Base Pair DNA Duplex=== | ||
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==See Also== | ==See Also== | ||
- | *[[Topoisomerase]] | + | *[[Topoisomerase|Topoisomerase]] |
==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:015801827</ref><references group="xtra"/> |
[[Category: DNA topoisomerase]] | [[Category: DNA topoisomerase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Drug]] | [[Category: Drug]] | ||
[[Category: Idenoisoquinoline]] | [[Category: Idenoisoquinoline]] | ||
+ | [[Category: Isomerase-dna complex]] | ||
[[Category: Poison]] | [[Category: Poison]] | ||
[[Category: Topoisomerase i]] | [[Category: Topoisomerase i]] |
Revision as of 01:50, 27 July 2012
Contents |
Human DNA Topoisomerase I (70 Kda) In Complex With The Indenoisoquinoline MJ-II-38 and Covalent Complex With A 22 Base Pair DNA Duplex
Template:ABSTRACT PUBMED 15801827
About this Structure
1sc7 is a 4 chain structure of Topoisomerase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Staker BL, Feese MD, Cushman M, Pommier Y, Zembower D, Stewart L, Burgin AB. Structures of three classes of anticancer agents bound to the human topoisomerase I-DNA covalent complex. J Med Chem. 2005 Apr 7;48(7):2336-45. PMID:15801827 doi:10.1021/jm049146p