1sc7

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[[Image:1sc7.png|left|200px]]
[[Image:1sc7.png|left|200px]]
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{{STRUCTURE_1sc7| PDB=1sc7 | SCENE= }}
{{STRUCTURE_1sc7| PDB=1sc7 | SCENE= }}
===Human DNA Topoisomerase I (70 Kda) In Complex With The Indenoisoquinoline MJ-II-38 and Covalent Complex With A 22 Base Pair DNA Duplex===
===Human DNA Topoisomerase I (70 Kda) In Complex With The Indenoisoquinoline MJ-II-38 and Covalent Complex With A 22 Base Pair DNA Duplex===
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{{ABSTRACT_PUBMED_15801827}}
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==See Also==
==See Also==
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*[[Topoisomerase]]
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*[[Topoisomerase|Topoisomerase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:15801827</ref><references group="xtra"/>
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<ref group="xtra">PMID:015801827</ref><references group="xtra"/>
[[Category: DNA topoisomerase]]
[[Category: DNA topoisomerase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Drug]]
[[Category: Drug]]
[[Category: Idenoisoquinoline]]
[[Category: Idenoisoquinoline]]
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[[Category: Isomerase-dna complex]]
[[Category: Poison]]
[[Category: Poison]]
[[Category: Topoisomerase i]]
[[Category: Topoisomerase i]]

Revision as of 01:50, 27 July 2012

Template:STRUCTURE 1sc7

Contents

Human DNA Topoisomerase I (70 Kda) In Complex With The Indenoisoquinoline MJ-II-38 and Covalent Complex With A 22 Base Pair DNA Duplex

Template:ABSTRACT PUBMED 15801827

About this Structure

1sc7 is a 4 chain structure of Topoisomerase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Staker BL, Feese MD, Cushman M, Pommier Y, Zembower D, Stewart L, Burgin AB. Structures of three classes of anticancer agents bound to the human topoisomerase I-DNA covalent complex. J Med Chem. 2005 Apr 7;48(7):2336-45. PMID:15801827 doi:10.1021/jm049146p

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