2r27

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{{Seed}}
 
[[Image:2r27.png|left|200px]]
[[Image:2r27.png|left|200px]]
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{{STRUCTURE_2r27| PDB=2r27 | SCENE= }}
{{STRUCTURE_2r27| PDB=2r27 | SCENE= }}
===Constitutively zinc-deficient mutant of human superoxide dismutase (SOD), C6A, H80S, H83S, C111S===
===Constitutively zinc-deficient mutant of human superoxide dismutase (SOD), C6A, H80S, H83S, C111S===
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{{ABSTRACT_PUBMED_17888947}}
{{ABSTRACT_PUBMED_17888947}}
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==Disease==
 
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Known disease associated with this structure: Amyotrophic lateral sclerosis, due to SOD1 deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147450 147450]]
 
==About this Structure==
==About this Structure==
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2R27 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R27 OCA].
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[[2r27]] is a 2 chain structure of [[Superoxide Dismutase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R27 OCA].
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==See Also==
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*[[Superoxide Dismutase|Superoxide Dismutase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:17888947</ref><references group="xtra"/>
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<ref group="xtra">PMID:017888947</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Superoxide dismutase]]
[[Category: Superoxide dismutase]]
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[[Category: Roberts, B R.]]
[[Category: Roberts, B R.]]
[[Category: Tainer, J A.]]
[[Category: Tainer, J A.]]
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[[Category: Acetylation]]
 
[[Category: Amyotrophic lateral sclerosis]]
[[Category: Amyotrophic lateral sclerosis]]
[[Category: Antioxidant]]
[[Category: Antioxidant]]
[[Category: Beta barrel]]
[[Category: Beta barrel]]
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[[Category: Copper]]
 
[[Category: Cu ion]]
[[Category: Cu ion]]
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[[Category: Cytoplasm]]
 
[[Category: Disease mutation]]
[[Category: Disease mutation]]
[[Category: Metal-binding]]
[[Category: Metal-binding]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]
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[[Category: Zinc]]
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 18:33:31 2009''
 

Revision as of 01:53, 27 July 2012

Template:STRUCTURE 2r27

Contents

Constitutively zinc-deficient mutant of human superoxide dismutase (SOD), C6A, H80S, H83S, C111S

Template:ABSTRACT PUBMED 17888947

About this Structure

2r27 is a 2 chain structure of Superoxide Dismutase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Roberts BR, Tainer JA, Getzoff ED, Malencik DA, Anderson SR, Bomben VC, Meyers KR, Karplus PA, Beckman JS. Structural characterization of zinc-deficient human superoxide dismutase and implications for ALS. J Mol Biol. 2007 Nov 2;373(4):877-90. Epub 2007 Aug 2. PMID:17888947 doi:http://dx.doi.org/10.1016/j.jmb.2007.07.043

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