3kxg

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[[Image:3kxg.png|left|200px]]
[[Image:3kxg.png|left|200px]]
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{{STRUCTURE_3kxg| PDB=3kxg | SCENE= }}
{{STRUCTURE_3kxg| PDB=3kxg | SCENE= }}
===Crystal structure of Z. mays CK2 kinase alpha subunit in complex with the inhibitor 3,4,5,6,7-pentabromo-1H-indazole (K64)===
===Crystal structure of Z. mays CK2 kinase alpha subunit in complex with the inhibitor 3,4,5,6,7-pentabromo-1H-indazole (K64)===
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{{ABSTRACT_PUBMED_21513497}}
{{ABSTRACT_PUBMED_21513497}}
==About this Structure==
==About this Structure==
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[[3kxg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Zea_mays Zea mays]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KXG OCA].
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[[3kxg]] is a 1 chain structure of [[Casein kinase]] with sequence from [http://en.wikipedia.org/wiki/Zea_mays Zea mays]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KXG OCA].
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==See Also==
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*[[Casein kinase|Casein kinase]]
==Reference==
==Reference==

Revision as of 02:01, 27 July 2012

Template:STRUCTURE 3kxg

Contents

Crystal structure of Z. mays CK2 kinase alpha subunit in complex with the inhibitor 3,4,5,6,7-pentabromo-1H-indazole (K64)

Template:ABSTRACT PUBMED 21513497

About this Structure

3kxg is a 1 chain structure of Casein kinase with sequence from Zea mays. Full crystallographic information is available from OCA.

See Also

Reference

  • Sarno S, Papinutto E, Franchin C, Bain J, Elliott M, Meggio F, Kazimierczuk Z, Orzeszko A, Zanotti G, Battistutta R, Pinna LA. Atp Site-Directed Inhibitors of Protein Kinase Ck2: An Update. Curr Top Med Chem. 2011 Mar 29. PMID:21513497
  • Battistutta R, Mazzorana M, Sarno S, Kazimierczuk Z, Zanotti G, Pinna LA. Inspecting the structure-activity relationship of protein kinase CK2 inhibitors derived from tetrabromo-benzimidazole. Chem Biol. 2005 Nov;12(11):1211-9. PMID:16298300 doi:10.1016/j.chembiol.2005.08.015
  • Battistutta R, Mazzorana M, Cendron L, Bortolato A, Sarno S, Kazimierczuk Z, Zanotti G, Moro S, Pinna LA. The ATP-binding site of protein kinase CK2 holds a positive electrostatic area and conserved water molecules. Chembiochem. 2007 Oct 15;8(15):1804-9. PMID:17768728 doi:10.1002/cbic.200700307

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