1o7p

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
(New page: 200px<br /> <applet load="1o7p" size="450" color="white" frame="true" align="right" spinBox="true" caption="1o7p, resolution 1.95&Aring;" /> '''NAPHTHALENE 1,2-DIO...)
Line 8: Line 8:
==About this Structure==
==About this Structure==
-
1O7P is a [[http://en.wikipedia.org/wiki/Protein_complex Protein complex]] structure of sequences from [[http://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]] with SO4, FE, EDO, NDH and FES as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.12.12 1.14.12.12]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1O7P OCA]].
+
1O7P is a [[http://en.wikipedia.org/wiki/Protein_complex Protein complex]] structure of sequences from [[http://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]] with SO4, FE, EDO, NDH and FES as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/Naphthalene_1,2-dioxygenase Naphthalene 1,2-dioxygenase]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.12.12 1.14.12.12]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1O7P OCA]].
==Reference==
==Reference==
Crystal structure of naphthalene dioxygenase: side-on binding of dioxygen to iron., Karlsson A, Parales JV, Parales RE, Gibson DT, Eklund H, Ramaswamy S, Science. 2003 Feb 14;299(5609):1039-42. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12586937 12586937]
Crystal structure of naphthalene dioxygenase: side-on binding of dioxygen to iron., Karlsson A, Parales JV, Parales RE, Gibson DT, Eklund H, Ramaswamy S, Science. 2003 Feb 14;299(5609):1039-42. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12586937 12586937]
 +
[[Category: Naphthalene 1,2-dioxygenase]]
[[Category: Protein complex]]
[[Category: Protein complex]]
[[Category: Pseudomonas putida]]
[[Category: Pseudomonas putida]]
Line 31: Line 32:
[[Category: oxidoreductase]]
[[Category: oxidoreductase]]
-
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Oct 29 21:31:18 2007''
+
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 14:04:54 2007''

Revision as of 12:00, 30 October 2007

Image:1o7p.gif

1o7p, resolution 1.95Å

Drag the structure with the mouse to rotate

NAPHTHALENE 1,2-DIOXYGENASE, PRODUCT COMPLEX

Overview

Binding of oxygen to iron is exploited in several biological and chemical, processes. Although computational and spectroscopic results have suggested, side-on binding, only end-on binding of oxygen to iron has been observed, in crystal structures. We have determined structures of naphthalene, dioxygenase that show a molecular oxygen species bound to the mononuclear, iron in a side-on fashion. In a complex with substrate and dioxygen, the, dioxygen molecule is lined up for an attack on the double bond of the, aromatic substrate. The structures reported here provide the basis for a, reaction mechanism and for the high stereospecificity of the reaction, catalyzed by naphthalene dioxygenase.

About this Structure

1O7P is a [Protein complex] structure of sequences from [Pseudomonas putida] with SO4, FE, EDO, NDH and FES as [ligands]. Active as [Naphthalene 1,2-dioxygenase], with EC number [1.14.12.12]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].

Reference

Crystal structure of naphthalene dioxygenase: side-on binding of dioxygen to iron., Karlsson A, Parales JV, Parales RE, Gibson DT, Eklund H, Ramaswamy S, Science. 2003 Feb 14;299(5609):1039-42. PMID:12586937

Page seeded by OCA on Tue Oct 30 14:04:54 2007

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1o7p"
Personal tools