3d0a

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Revision as of 02:25, 27 July 2012

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Template:STRUCTURE 3d0a

Contents 1 Human p53 core domain with hot spot mutation R249S and second site suppressor mutation H168R in sequence-specific complex with DNA 2 About this Structure 3 See Also 4 Reference

Human p53 core domain with hot spot mutation R249S and second site suppressor mutation H168R in sequence-specific complex with DNA

Template:ABSTRACT PUBMED 18996393

About this Structure

3d0a is a 8 chain structure of P53 with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• P53

Reference

• Suad O, Rozenberg H, Brosh R, Diskin-Posner Y, Kessler N, Shimon LJ, Frolow F, Liran A, Rotter V, Shakked Z. Structural basis of restoring sequence-specific DNA binding and transactivation to mutant p53 by suppressor mutations. J Mol Biol. 2009 Jan 9;385(1):249-65. Epub 2008 Oct 30. PMID:18996393 doi:10.1016/j.jmb.2008.10.063