3qtf
From Proteopedia
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[[Image:3qtf.png|left|200px]] | [[Image:3qtf.png|left|200px]] | ||
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{{STRUCTURE_3qtf| PDB=3qtf | SCENE= }} | {{STRUCTURE_3qtf| PDB=3qtf | SCENE= }} | ||
===Design and SAR of macrocyclic Hsp90 inhibitors with increased metabolic stability and potent cell-proliferation activity=== | ===Design and SAR of macrocyclic Hsp90 inhibitors with increased metabolic stability and potent cell-proliferation activity=== | ||
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{{ABSTRACT_PUBMED_21420297}} | {{ABSTRACT_PUBMED_21420297}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3qtf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QTF OCA]. | + | [[3qtf]] is a 1 chain structure of [[Heat Shock Proteins]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QTF OCA]. |
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| + | ==See Also== | ||
| + | *[[Heat Shock Proteins|Heat Shock Proteins]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:021420297</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Bloom, J D.]] | [[Category: Bloom, J D.]] | ||
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[[Category: Vogan, E M.]] | [[Category: Vogan, E M.]] | ||
[[Category: Zapf, C W.]] | [[Category: Zapf, C W.]] | ||
| + | [[Category: Atp binding domain]] | ||
| + | [[Category: Atp-binding]] | ||
| + | [[Category: Chaperone]] | ||
| + | [[Category: Chaperone-chaperone inhibitor complex]] | ||
| + | [[Category: Nucleotide-binding]] | ||
| + | [[Category: Phosphoprotein]] | ||
| + | [[Category: Stress response]] | ||
Revision as of 02:32, 27 July 2012
Contents |
Design and SAR of macrocyclic Hsp90 inhibitors with increased metabolic stability and potent cell-proliferation activity
Template:ABSTRACT PUBMED 21420297
About this Structure
3qtf is a 1 chain structure of Heat Shock Proteins with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Zapf CW, Bloom JD, McBean JL, Dushin RG, Nittoli T, Ingalls C, Sutherland AG, Sonye JP, Eid CN, Golas J, Liu H, Boschelli F, Hu Y, Vogan E, Levin JI. Design and SAR of macrocyclic Hsp90 inhibitors with increased metabolic stability and potent cell-proliferation activity. Bioorg Med Chem Lett. 2011 Apr 15;21(8):2278-82. Epub 2011 Feb 28. PMID:21420297 doi:10.1016/j.bmcl.2011.02.101
Categories: Homo sapiens | Bloom, J D. | Boschelli, F. | Dushin, R G. | Eid, C N. | Golas, J. | Hu, Y. | Ingalls, C. | Levin, J I. | Liu, H. | McBean, J L. | Nittoli, T. | Sonye, J P. | Sutherland, A G. | Vogan, E M. | Zapf, C W. | Atp binding domain | Atp-binding | Chaperone | Chaperone-chaperone inhibitor complex | Nucleotide-binding | Phosphoprotein | Stress response
