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2rgp

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Revision as of 02:35, 27 July 2012

Image:2rgp.png

Template:STRUCTURE 2rgp

Contents

Structure of EGFR in complex with hydrazone, a potent dual inhibitor

Template:ABSTRACT PUBMED 18653333

About this Structure

2rgp is a 1 chain structure of Epidermal Growth Factor Receptor with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Xu G, Abad MC, Connolly PJ, Neeper MP, Struble GT, Springer BA, Emanuel SL, Pandey N, Gruninger RH, Adams M, Moreno-Mazza S, Fuentes-Pesquera AR, Middleton SA. 4-Amino-6-arylamino-pyrimidine-5-carbaldehyde hydrazones as potent ErbB-2/EGFR dual kinase inhibitors. Bioorg Med Chem Lett. 2008 Aug 15;18(16):4615-9. Epub 2008 Jul 10. PMID:18653333 doi:10.1016/j.bmcl.2008.07.020

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OCA

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