3ka0

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{{STRUCTURE_3ka0| PDB=3ka0 | SCENE= }}
{{STRUCTURE_3ka0| PDB=3ka0 | SCENE= }}
===MK2 complex with inhibitor 6-(5-(2-aminopyrimidin-4-ylamino)-2-hydroxyphenyl)-N-methylbenzo[b]thiophene-2-carboxamide===
===MK2 complex with inhibitor 6-(5-(2-aminopyrimidin-4-ylamino)-2-hydroxyphenyl)-N-methylbenzo[b]thiophene-2-carboxamide===
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{{ABSTRACT_PUBMED_19919896}}
{{ABSTRACT_PUBMED_19919896}}
==About this Structure==
==About this Structure==
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3KA0 is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KA0 OCA].
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[[3ka0]] is a 1 chain structure of [[Mitogen-activated protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KA0 OCA].
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==See Also==
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*[[Mitogen-activated protein kinase|Mitogen-activated protein kinase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:19919896</ref><references group="xtra"/>
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<ref group="xtra">PMID:019919896</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Tnfalpha]]
[[Category: Tnfalpha]]
[[Category: Transferase]]
[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 12 10:30:20 2010''
 

Revision as of 02:59, 27 July 2012

Template:STRUCTURE 3ka0

Contents

MK2 complex with inhibitor 6-(5-(2-aminopyrimidin-4-ylamino)-2-hydroxyphenyl)-N-methylbenzo[b]thiophene-2-carboxamide

Template:ABSTRACT PUBMED 19919896

About this Structure

3ka0 is a 1 chain structure of Mitogen-activated protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Argiriadi MA, Ericsson AM, Harris CM, Banach DL, Borhani DW, Calderwood DJ, Demers MD, Dimauro J, Dixon RW, Hardman J, Kwak S, Li B, Mankovich JA, Marcotte D, Mullen KD, Ni B, Pietras M, Sadhukhan R, Sousa S, Tomlinson MJ, Wang L, Xiang T, Talanian RV. 2,4-Diaminopyrimidine MK2 inhibitors. Part I: Observation of an unexpected inhibitor binding mode. Bioorg Med Chem Lett. 2010 Jan 1;20(1):330-3. Epub 2009 Oct 29. PMID:19919896 doi:10.1016/j.bmcl.2009.10.102

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