3exo
From Proteopedia
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{{STRUCTURE_3exo| PDB=3exo | SCENE= }} | {{STRUCTURE_3exo| PDB=3exo | SCENE= }} | ||
===Crystal structure of BACE1 bound to inhibitor=== | ===Crystal structure of BACE1 bound to inhibitor=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[3exo]] is a 1 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EXO OCA]. | |
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| + | ==See Also== | ||
| + | *[[Beta secretase|Beta secretase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019036583</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Memapsin 2]] | [[Category: Memapsin 2]] | ||
[[Category: Allison, T J.]] | [[Category: Allison, T J.]] | ||
| - | [[Category: Alternative splicing]] | ||
[[Category: Aspartyl protease]] | [[Category: Aspartyl protease]] | ||
[[Category: Bace 1]] | [[Category: Bace 1]] | ||
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[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
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Revision as of 04:22, 27 July 2012
Contents |
Crystal structure of BACE1 bound to inhibitor
Template:ABSTRACT PUBMED 19036583
About this Structure
3exo is a 1 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Steele TG, Hills ID, Nomland AA, de Leon P, Allison T, McGaughey G, Colussi D, Tugusheva K, Haugabook SJ, Espeseth AS, Zuck P, Graham SL, Stachel SJ. Identification of a small molecule beta-secretase inhibitor that binds without catalytic aspartate engagement. Bioorg Med Chem Lett. 2009 Jan 1;19(1):17-20. Epub 2008 Nov 13. PMID:19036583 doi:10.1016/j.bmcl.2008.11.027
Categories: Homo sapiens | Memapsin 2 | Allison, T J. | Aspartyl protease | Bace 1 | Beta secretase | Glycoprotein | Hydrolase | Membrane | Protease | Transmembrane | Zymogen
