2od3
From Proteopedia
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[[Image:2od3.png|left|200px]] | [[Image:2od3.png|left|200px]] | ||
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{{STRUCTURE_2od3| PDB=2od3 | SCENE= }} | {{STRUCTURE_2od3| PDB=2od3 | SCENE= }} | ||
===Human thrombin chimera with human residues 184a, 186, 186a, 186b, 186c and 222 replaced by murine thrombin equivalents.=== | ===Human thrombin chimera with human residues 184a, 186, 186a, 186b, 186c and 222 replaced by murine thrombin equivalents.=== | ||
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{{ABSTRACT_PUBMED_17428793}} | {{ABSTRACT_PUBMED_17428793}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Dysprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hyperprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hypoprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2od3]] is a 2 chain structure of [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OD3 OCA]. | |
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| + | ==See Also== | ||
| + | *[[Thrombin|Thrombin]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017428793</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Bush, L A.]] | [[Category: Bush, L A.]] | ||
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[[Category: Marino, F.]] | [[Category: Marino, F.]] | ||
[[Category: Mathews, F S.]] | [[Category: Mathews, F S.]] | ||
| + | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
[[Category: Serine protease]] | [[Category: Serine protease]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 21:10:39 2009'' | ||
Revision as of 04:47, 27 July 2012
Contents |
Human thrombin chimera with human residues 184a, 186, 186a, 186b, 186c and 222 replaced by murine thrombin equivalents.
Template:ABSTRACT PUBMED 17428793
About this Structure
2od3 is a 2 chain structure of Thrombin with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Marino F, Chen ZW, Ergenekan CE, Bush-Pelc LA, Mathews FS, Di Cera E. Structural basis of Na+ activation mimicry in murine thrombin. J Biol Chem. 2007 Jun 1;282(22):16355-61. Epub 2007 Apr 10. PMID:17428793 doi:http://dx.doi.org/10.1074/jbc.M701323200
