3kli
From Proteopedia
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[[Image:3kli.png|left|200px]] | [[Image:3kli.png|left|200px]] | ||
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{{STRUCTURE_3kli| PDB=3kli | SCENE= }} | {{STRUCTURE_3kli| PDB=3kli | SCENE= }} | ||
===Crystal structure of unliganded AZT-resistant HIV-1 Reverse Transcriptase=== | ===Crystal structure of unliganded AZT-resistant HIV-1 Reverse Transcriptase=== | ||
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{{ABSTRACT_PUBMED_20852643}} | {{ABSTRACT_PUBMED_20852643}} | ||
==About this Structure== | ==About this Structure== | ||
- | [[3kli]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KLI OCA]. | + | [[3kli]] is a 2 chain structure of [[AZT-resistant HIV-1 reverse transcriptase]] and [[Reverse transcriptase]] with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KLI OCA]. |
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+ | ==See Also== | ||
+ | *[[AZT-resistant HIV-1 reverse transcriptase|AZT-resistant HIV-1 reverse transcriptase]] | ||
+ | *[[Reverse transcriptase|Reverse transcriptase]] | ||
==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:020852643</ref><references group="xtra"/> |
[[Category: Human immunodeficiency virus 1]] | [[Category: Human immunodeficiency virus 1]] | ||
[[Category: Arnold, E.]] | [[Category: Arnold, E.]] | ||
[[Category: Sarafianos, S G.]] | [[Category: Sarafianos, S G.]] | ||
[[Category: Tu, X.]] | [[Category: Tu, X.]] | ||
+ | [[Category: Aid]] | ||
+ | [[Category: Azt]] | ||
+ | [[Category: Azt resistance]] | ||
+ | [[Category: Azt resistance mechanism]] | ||
+ | [[Category: Azt resistance mutation]] | ||
+ | [[Category: Dna polymerase]] | ||
+ | [[Category: Dna recombination]] | ||
+ | [[Category: Hetero dimer]] | ||
+ | [[Category: Hiv]] | ||
+ | [[Category: Multifunctional enzyme]] | ||
+ | [[Category: Nrti]] | ||
+ | [[Category: Nucleoside inhibitor]] | ||
+ | [[Category: P51/p66]] | ||
+ | [[Category: Reverse transcriptase]] | ||
+ | [[Category: Rna-directed dna polymerase]] | ||
+ | [[Category: Transferase]] |
Revision as of 05:25, 27 July 2012
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3kli, resolution 2.65Å () | |||||||
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Gene: | gag-pol (Human immunodeficiency virus 1) | ||||||
Related: | 3kle, 3klf, 3klg, 3klh | ||||||
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Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
Coordinates: | save as pdb, mmCIF, xml |
Contents |
Crystal structure of unliganded AZT-resistant HIV-1 Reverse Transcriptase
Template:ABSTRACT PUBMED 20852643
About this Structure
3kli is a 2 chain structure of AZT-resistant HIV-1 reverse transcriptase and Reverse transcriptase with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.
See Also
Reference
- Tu X, Das K, Han Q, Bauman JD, Clark AD Jr, Hou X, Frenkel YV, Gaffney BL, Jones RA, Boyer PL, Hughes SH, Sarafianos SG, Arnold E. Structural basis of HIV-1 resistance to AZT by excision. Nat Struct Mol Biol. 2010 Oct;17(10):1202-9. Epub 2010 Sep 19. PMID:20852643 doi:10.1038/nsmb.1908
Categories: Human immunodeficiency virus 1 | Arnold, E. | Sarafianos, S G. | Tu, X. | Aid | Azt | Azt resistance | Azt resistance mechanism | Azt resistance mutation | Dna polymerase | Dna recombination | Hetero dimer | Hiv | Multifunctional enzyme | Nrti | Nucleoside inhibitor | P51/p66 | Reverse transcriptase | Rna-directed dna polymerase | Transferase