This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3en6
From Proteopedia
| Line 1: | Line 1: | ||
| - | {{Seed}} | ||
[[Image:3en6.png|left|200px]] | [[Image:3en6.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_3en6", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_3en6| PDB=3en6 | SCENE= }} | {{STRUCTURE_3en6| PDB=3en6 | SCENE= }} | ||
===Targeted polypharmacology: crystal structure of the c-Src kinase domain in complex with PP102, a multitargeted kinase inhibitor=== | ===Targeted polypharmacology: crystal structure of the c-Src kinase domain in complex with PP102, a multitargeted kinase inhibitor=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_18849971}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 18849971 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_18849971}} | {{ABSTRACT_PUBMED_18849971}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3en6]] is a 2 chain structure of [[Proto-oncogene tyrosine-protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EN6 OCA]. | |
| + | |||
| + | ==See Also== | ||
| + | *[[Proto-oncogene tyrosine-protein kinase|Proto-oncogene tyrosine-protein kinase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018849971</ref><references group="xtra"/> |
[[Category: Gallus gallus]] | [[Category: Gallus gallus]] | ||
[[Category: Non-specific protein-tyrosine kinase]] | [[Category: Non-specific protein-tyrosine kinase]] | ||
| Line 30: | Line 21: | ||
[[Category: Knight, Z A.]] | [[Category: Knight, Z A.]] | ||
[[Category: Shokat, K M.]] | [[Category: Shokat, K M.]] | ||
| - | [[Category: Alternative splicing]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
[[Category: Inhibitor]] | [[Category: Inhibitor]] | ||
| Line 51: | Line 41: | ||
[[Category: Tyrosine]] | [[Category: Tyrosine]] | ||
[[Category: Tyrosine-protein kinase]] | [[Category: Tyrosine-protein kinase]] | ||
| - | |||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 21:57:17 2009'' | ||
Revision as of 05:55, 27 July 2012
Contents |
Targeted polypharmacology: crystal structure of the c-Src kinase domain in complex with PP102, a multitargeted kinase inhibitor
Template:ABSTRACT PUBMED 18849971
About this Structure
3en6 is a 2 chain structure of Proto-oncogene tyrosine-protein kinase with sequence from Gallus gallus. Full crystallographic information is available from OCA.
See Also
Reference
- Apsel B, Blair JA, Gonzalez B, Nazif TM, Feldman ME, Aizenstein B, Hoffman R, Williams RL, Shokat KM, Knight ZA. Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases. Nat Chem Biol. 2008 Nov;4(11):691-9. Epub 2008 Oct 12. PMID:18849971 doi:http://dx.doi.org/10.1038/nchembio.117
Categories: Gallus gallus | Non-specific protein-tyrosine kinase | Apsel, B. | Blair, J A. | Knight, Z A. | Shokat, K M. | Atp-binding | Inhibitor | Kinase | Kinase-inhibitor complex | Lipoprotein | Multitarget | Myristate | Nucleotide-binding | Phosphoinositide | Phosphoprotein | Polypharmacology | Proto-oncogene | Pyrazolopyrimidine | Sh2 domain | Sh3 domain | Signaling | Src | Transferase | Tyrosine | Tyrosine-protein kinase
