3gol

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Revision as of 06:12, 27 July 2012

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Template:STRUCTURE 3gol

Contents 1 HCV NS5b polymerase in complex with 1,5 benzodiazepine inhibitor (R)-11d 2 About this Structure 3 See Also 4 Reference

HCV NS5b polymerase in complex with 1,5 benzodiazepine inhibitor (R)-11d

Template:ABSTRACT PUBMED 19342234

About this Structure

3gol is a 2 chain structure of RNA polymerase with sequence from Hepatitis c virus isolate. Full crystallographic information is available from OCA.

See Also

• RNA polymerase

Reference

• McGowan D, Nyanguile O, Cummings MD, Vendeville S, Vandyck K, Van den Broeck W, Boutton CW, De Bondt H, Quirynen L, Amssoms K, Bonfanti JF, Last S, Rombauts K, Tahri A, Hu L, Delouvroy F, Vermeiren K, Vandercruyssen G, Van der Helm L, Cleiren E, Mostmans W, Lory P, Pille G, Van Emelen K, Fanning G, Pauwels F, Lin TI, Simmen K, Raboisson P. 1,5-Benzodiazepine inhibitors of HCV NS5B polymerase. Bioorg Med Chem Lett. 2009 May 1;19(9):2492-6. Epub 2009 Mar 14. PMID:19342234 doi:10.1016/j.bmcl.2009.03.035