3igb
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | {{Seed}} | ||
[[Image:3igb.png|left|200px]] | [[Image:3igb.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_3igb", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_3igb| PDB=3igb | SCENE= }} | {{STRUCTURE_3igb| PDB=3igb | SCENE= }} | ||
===Bace-1 with Compound 3=== | ===Bace-1 with Compound 3=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_19757823}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 19757823 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_19757823}} | {{ABSTRACT_PUBMED_19757823}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3igb]] is a 1 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IGB OCA]. | |
| + | |||
| + | ==See Also== | ||
| + | *[[Beta secretase|Beta secretase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019757823</ref><ref group="xtra">PMID:019968289</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Memapsin 2]] | [[Category: Memapsin 2]] | ||
[[Category: Olland, A M.]] | [[Category: Olland, A M.]] | ||
| - | [[Category: Alternative splicing]] | ||
[[Category: Amino-imidazole]] | [[Category: Amino-imidazole]] | ||
[[Category: Aspartyl protease]] | [[Category: Aspartyl protease]] | ||
| Line 36: | Line 26: | ||
[[Category: Inhibitor]] | [[Category: Inhibitor]] | ||
[[Category: Membrane]] | [[Category: Membrane]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Protease]] | [[Category: Protease]] | ||
| - | [[Category: Structure]] | ||
[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
| - | |||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jan 28 15:14:04 2010'' | ||
Revision as of 07:07, 27 July 2012
Contents |
Bace-1 with Compound 3
Template:ABSTRACT PUBMED 19757823
About this Structure
3igb is a 1 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Malamas MS, Erdei J, Gunawan I, Barnes K, Johnson M, Hui Y, Turner J, Hu Y, Wagner E, Fan K, Olland A, Bard J, Robichaud AJ. Aminoimidazoles as potent and selective human beta-secretase (BACE1) inhibitors. J Med Chem. 2009 Oct 22;52(20):6314-23. PMID:19757823 doi:10.1021/jm9006752
- Malamas MS, Erdei J, Gunawan I, Turner J, Hu Y, Wagner E, Fan K, Chopra R, Olland A, Bard J, Jacobsen S, Magolda RL, Pangalos M, Robichaud AJ. Design and synthesis of 5,5'-disubstituted aminohydantoins as potent and selective human beta-secretase (BACE1) inhibitors. J Med Chem. 2010 Feb 11;53(3):1146-58. PMID:19968289 doi:10.1021/jm901414e
Categories: Homo sapiens | Memapsin 2 | Olland, A M. | Amino-imidazole | Aspartyl protease | Bace-1 | Disulfide bond | Glycoprotein | Hydrolase | Inhibitor | Membrane | Protease | Transmembrane | Zymogen
